Compounds for the treatment of pathologies associated with aging and degenerative disorders
The present invention relates to methods of inhibiting one or more signs of aging and/or degenerative disorder in a subject in need of such treatment, which comprise administering, to the subject, an effective amount of one or more of the compounds as set forth herein. “Inhibiting a sign of aging or degenerative disorder” means reducing the risk of occurrence, delaying the onset, slowing the progression, and/or reducing the severity and/or manifestation, of a sign of aging or degenerative disorder, and includes, but is not limited to, preventing the occurrence, development or progression of a sign of aging or degenerative disorder.
1. A method of inhibiting free radical damage in a subject with Huntington's Disease or progeria, comprising administering to the subject an effective amount of a compound that reduces free radical damage in the mitochondria of the subject, wherein the compound is selected from
2. The method of claim 1 , wherein the subject has Huntington's Disease.
3. The method of claim 2 , and the compound that is administered to the subject is
4. The method of claim 1 , wherein the subject has progeria.
5. The method of claim 4 , wherein the compound that is administered to the subject is