Topical parasiticide composition
A topical parasiticide composition comprising: (i) a phenyl pyrazole insecticide; and/or a neonicotinoid; (ii) a macrocylic lactone and/or an aminoacetonitrile derivatives; (iii) an Insect Growth Regulator; and (iv) a 2-acyl-4-oxo-1,2,3,6,7,11b-4H-pyrazino[2,1a]isoquinoline derivative.
1. A spot-on or pour-on composition for the treatment of endo- and ecto-parasites comprising:
(i) from 0.1 to 10% (w/v) of Fipronil based on the total volume of the composition;
(ii) from 0.1 to 10% (w/v) of a macrocyclic lactone based on the total volume of the composition;
(iii) from 0.1 to 10% (w/v) of Methoprene based on the total volume of the composition;
(iv) from 0.1 to 10% (w/v) of Praziquantel based on the total volume of the composition; and
wherein the composition comprises an alcohol solvent.
2. The composition of claim 1 wherein the macrocyclic lactone is Moxidectin.
3. The composition of claim 1 comprising Fipronil, Moxidectin, S-methoprene and Praziquantel.
4. The composition according to claim 1 wherein the composition comprises at least 60% (w/v) of solvent based on the total volume of the composition.
5. A composition according to claim 1 comprising at least one adjuvant selected from anti-oxidants, crystallization inhibitor and other actives.
6. A composition according to claim 1 which is in the form of a spray-on formulation.
7. A method of treating a human or animal infected with endo and ecto parasiticides, the method comprising applying to the skin of the infected human or animal the composition as defined in claim 1 .