IP Library Granted Patent US 9,237,989
Granted Patent B2
US 9,237,989 · App. 13/322,226 · Granted Jan 19, 2016

Coating method

Inventors: Rehan Ahmed (Edinburgh, GB); Gerardus Hendricus Markx (Kirknewton, GB)
Assignee: Taragenyx Limited
A61K6/0067A61K9/1676A61K31/43B22F1/02B22F1/025C09D1/00C23C4/065C23C24/04Y10T428/25Y10T428/252Y10T428/254Y10T428/256Y10T428/258Y10T428/2991
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Quick Facts
Patent No.
US 9,237,989
App. No.
13/322,226
Granted
Jan 19, 2016
Kind
B2
Abstract

A method of coating an article includes the steps of providing a powder comprising coated particles; and spray coating the powder onto a surface of the article to form a composite coating. The spray coating may be carried out by combustion spraying, gas plasma spraying, including vacuum plasma spraying (VPS), and cold spraying. The article may be an implant for surgical or dental use. The powder may include particles of metal coated calcium phosphates, especially metal coated hydroxyapatite. The particles may include bioactive agents.

Claims (18)

1. A method of coating an article comprising the steps of:

providing a powder comprising coated particles; and spray coating the powder onto a surface of said article to form a composite coating,

wherein the article core comprises or consists of a calcium phosphate and the coated particles comprise a metal coating.

2. The method of claim 1 wherein the metal coating comprises or consists of titanium or a titanium alloy.

3. The method of claim 1 wherein the coating on the coated particles has been formed by a vapour deposition process.

4. The method of claim 1 wherein the spray coating technique employed is selected from the group consisting of combustion spraying, gas plasma spraying, and cold spraying.

5. The method of claim 4 wherein the gas plasma spraying is vacuum plasma spraying.

6. The method of claim 1 wherein the particle core comprises or consists of hydroxyapatite.

7. The method of claim 1 wherein the powder for spray coating further comprises a bioactive agent.

8. The method of claim 7 wherein the bioactive agent is incorporated in the coated particles.

9. The method of claim 8 wherein the bioactive agent is incorporated in the particle core material.

10. The method of claim 9 wherein the bioactive agent is incorporated in the particle core material by:

mixing the bioactive agent with core material when forming the cores; or

impregnating porous cores with the bioactive agent before coating to form coated particles; or

by impregnating porous cores of coated particles with the bioactive agent, when the particle coating is partial or is porous to the bioactive agent.

11. The method of claim 7 wherein the bioactive agent is selected from the group consisting of antibiotics, anti-tumour drugs, anti-inflammatory drugs, adhesion factors, growth factors and morphogens.

12. The method of claim 11 wherein the adhesion factor is fibronectin.

13. The method of claim 11 wherein the growth factor is a Bone Morphogenetic Protein.

Assignments (6)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 16, 2016
From: AHMED, REHAN; MARKX, GERARDUS HENDRICUS
To: BEDI, KATHRYN JANE
Reel/Frame 038935/0891 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 16, 2016
From: BEDI, KATHRYN JANE
To: RRG COATINGS LIMITED
Reel/Frame 038935/0915 →
CHANGE OF NAME Recorded Jun 16, 2016
From: RRG COATINGS LIMITED
To: TARAGENYX LIMITED
Reel/Frame 038935/0918 →
CHANGE OF NAME Recorded Jul 15, 2013
From: RRG COATINGS LIMITED
To: TARAGENYX LIMITED
Reel/Frame 030799/0497 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded May 7, 2012
From: BEDI, KATHRYN JANE
To: RRG COATINGS LIMITED
Reel/Frame 028165/0678 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded May 3, 2012
From: AHMED, REHAN; MARKX, GERARDUS HENDRICUS
To: BEDI, KATHRYN JANE
Reel/Frame 028151/0149 →
Priority Claims (1)
GB 0909183.6 · May 28, 2009 · national
Continuity (1)
Related Publication 20120141775A1 · Jun 7, 2012