Nozzle and inhaler and method for producing a nozzle
A nozzle, an inhaler with a nozzle and a method for producing a nozzle are proposed, which nozzle comprises two holes formed in a flat plate which plate is then deformed such that the axes of the holes intersect so that jets of fluids moving through the holes impinge with each other.
1. A nozzle for dispensing a fluid for inhalation, the nozzle comprising:
a plate having only two holes, wherein the two holes are circular in cross section, have a hydraulic diameter between 5 and 15 μm, are formed perpendicular to a surface of the plate, taper towards an outlet side of the nozzle forming a natural cone with an essentially constant taper angle of about 5 to 20 degrees from an inlet side of the nozzle to the inlet side of the nozzle such that a diameter of the two holes at the outlet side is smaller than a diameter of the two holes at an inlet side of the nozzle wherein,
the plate is deformed having a curved depression between two generally flat regions of the plate such that respective axes of the two holes intersect with each other at the outlet side of the nozzle so that respective jets of fluid exiting the two holes impact with each other at a position of impact when the fluid is dispensed, and
the diameters and orientation of the two holes is such that impact of the respective jets of fluid generate an aerosol of a shape that expands significantly as a function of an increasing distance from the position of impact such that the resulting aerosol is suitable for patient inhalation of the dispensed fluid.
2. The nozzle according to claim 1 , wherein the plate is made of metal.
3. The nozzle according to claim 1 , wherein the plate has a thickness of less than 200 μm.
4. The nozzle according to claim 1 , wherein the two holes are located on opposite sides of the curved depression.
5. The nozzle according to claim 1 , wherein a distance between the two holes is about between 30 and 300 μm.
6. An inhaler for dispensing of an inhalation formulation as an aerosol, comprising:
a conveying means for conveying a fluid from a source;
a nozzle for dispensing the fluid for inhalation, the nozzle comprising a plate with only two holes, wherein the two holes are circular in cross section, have a hydraulic diameter between 5 and 15 μm, are formed perpendicular to a surface of the plate, taper towards an outlet side of the nozzle forming a natural cone with an essentially constant taper angle of about 5 to 20 degrees from an inlet side of the nozzle to the outlet side of the nozzle such that a diameter of the two holes at the outlet side is smaller than a diameter of the two holes at the inlet side of the nozzle, wherein:
the plate is deformed having a curved depression between two generally flat regions of the plate such that respective axes of the two holes intersect with each other at the outlet side of the nozzle so that respective jets of fluid exiting the two holes impact with each other at a position of impact when the fluid is dispensed, and
the diameters and orientation of the two holes is such that impact of the respective jets of fluid generate an aerosol of a shape that expands significantly as a function of an increasing distance from the position of impact such that the resulting aerosol is suitable for patient inhalation of the dispensed fluid.