Granted Patent
B2
US 9,260,381 · App. 14/730,994 · Granted Feb 16, 2016
Pyrazolopyridazines and methods for treating retinal degenerative diseases and hearing loss associated with usher syndrome
Inventors:
Roland Werner Bürli (Bishop's Stortford, GB); William Rameshchandra Krishna Esmieu (Cambridge, GB); Christopher James Lock (Burwell, GB); Karine Fabienne Malagu (Saffron Walden, GB); Andrew Pate Owens (Huntingdon, GB); William E Harte (Moorpark, CA)
Assignee:
USHER III INITIATIVE, INC.
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Abstract
Compounds, compositions and methods for the treatment of retinal degenerative diseases, such as retinitis pigmentosa, Leber's congenital Amaurosis, Syndromic retinal degenerations, age-related macular degeneration and Usher Syndrome, and hearing loss associated with Usher Syndrome are described herein.
Claims (3)
1. A compound having the structure:
or a pharmaceutically acceptable salt thereof.
2. A composition comprising a compound or pharmaceutically acceptable salt of the compound of claim 1 , and a pharmaceutically acceptable carrier or vehicle.
Assignments (3)
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded Dec 17, 2015
From: HARTE, WILLIAM E
To: USHER III INITIATIVE, INC.
Reel/Frame 037319/0129 →
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded Dec 17, 2015
From: BURLI, ROLAND WERNER; KRISHNA ESMIEU, WILLIAM RAMESHCHANDRA; LOCK, CHRISTOPHER JAMES; MALAGU, KARINE FABIENNE; OWENS, ANDREW PATE
To: BIOFOCUS DPI LTD.
Reel/Frame 037319/0137 →
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded Dec 17, 2015
From: BIOFOCUS DPI LTD.
To: USHER III INITIATIVE, INC.
Reel/Frame 037319/0161 →
Continuity (6)
Continuation
PCTUS2012034959
· Apr 25, 2012
Provisional Application
61576471
· Dec 16, 2011
Provisional Application
61537908
· Sep 22, 2011
Provisional Application
61478642
· Apr 25, 2011