IP Library Granted Patent US 9,273,152
Granted Patent B2
US 9,273,152 · App. 14/562,849 · Granted Mar 1, 2016

Compositions comprising fibrous polypeptides and polysaccharides

Inventors: Oded Shoseyov (Karme Yosef, IL); Shaul Lapidot (Kibbutz Tzora, IL); Sigal Meirovitch (Tel-Aviv, IL); Daniel L Siegel (Rechovot, IL)
Assignees: Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.; CollPlant Ltd.
C08B15/06B01J19/127C07K14/43518C07K14/43563C07K14/43586C07K14/43595C07K14/75C07K17/10C08B15/005C08L89/00C12N15/8257B01J2219/1203C07K2319/20
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Quick Facts
Patent No.
US 9,273,152
App. No.
14/562,849
Granted
Mar 1, 2016
Kind
B2
Abstract

Isolated polypeptides are disclosed comprising an amino acid sequence encoding a monomer of a fibrous polypeptide attached to a heterologous polysaccharide binding domain. Composites comprising same, methods of generating same and uses thereof are all disclosed.

Claims (7)

1. A composite comprising resilin and cellulose, wherein said cellulose is in the form of whiskers.

2. A composite comprising a fibrous polypeptide and cellulose, said fibrous polypeptide comprising a heterologous polysaccharide binding domain, the composite being non-immobilized, wherein said cellulose is in the form of whiskers.

3. The composite of claim 1 , wherein said resilin comprises a cellulose binding domain.

4. The composite of claim 1 , further comprising an additional polypeptide being selected from the group consisting of mussel byssus protein, silkworm silk protein, spider silk protein, collagen, elastin and fragments thereof.

5. The composite of claim 1 being crosslinked.

6. The composite of claim 1 being non-crosslinked.

7. The composite of claim 1 , wherein said resilin comprises at least two repeating units of the sequence as set forth in SEQ ID NO: 45.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 22, 2015
From: SIEGEL, DANIEL L
To: COLLPLANT LTD.
Reel/Frame 035000/0834 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 22, 2015
From: SHOSEYOV, ODED; LAPIDOT, SHAUL; MEIROVITCH, SIGAL
To: YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD.
Reel/Frame 035060/0307 →
Continuity (5)
Division 13870032 · Apr 25, 2013
Division 12744703
Provisional Application 61071968 · May 28, 2008
Provisional Application 60996581 · Nov 26, 2007
Related Publication 20150094452A1 · Apr 2, 2015