Micropore forming apparatus and micropore forming method
To provide a micropore forming apparatus capable of increasing the amount of interstitial fluid extracted from micropores formed in the skin of a subject. The micropore forming apparatus includes a skin contact part that has a plurality of microneedles for piercing the skin of the subject, and a force exerting part for exerting a force on the skin contact part toward the skin of the subject. The force exerting part is configured so as to exert a force on the microneedles toward the skin at a position at which the microneedles of the skin contact part are to pierce the skin of the subject.
1. A micropore forming apparatus for forming micropores in the skin by piercing the skin of a subject with microneedles comprising:
a skin contact part that has a plurality of microneedles for piercing the skin of the subject; and
a spring for exerting a force on the skin contact part toward the skin of the subject;
wherein the spring has a length so as to maintain the state of compression of the spring and thereby maintain the state of the microneedles being pressed into the skin after the microneedles have initially pierced the skin of the subject,
wherein, after the microneedles have pierced the skin, the spring exerts a force P (Pa) on the skin through the microneedles such that 2.56×10 5 ≦P.
2. The micropore forming apparatus of claim 1 , wherein the speed S (m/s) of the microneedles piercing the skin is set such that 4.8≦S.
3. The micropore forming apparatus of claim 1 , wherein the speed S (m/s) of the microneedles piercing the skin is set such that S is ≦6.1.
4. A micropore forming method for forming micropores in the skin of a subject using a micropore forming apparatus for forming micropores in the skin by piercing the skin of the subject with microneedles;
wherein the micropore forming apparatus comprises:
a skin contact part that has a plurality of microneedles for piercing the skin of the subject; and
a spring for exerting a force on the skin contact part toward the skin of the subject;
wherein the spring has a length so as to maintain the state of compression of the spring and thereby maintain the state of the microneedles being pressed into the skin after the microneedles have initially pierced the skin of the subject,
the method further comprising collecting interstitial fluid extracted from the micropores by an extraction medium.
5. The micropore forming method of claim 4 , wherein the predetermined time is 0.15 second or longer.
6. The micropore forming method of claim 5 , wherein the predetermined time is 60 seconds or less.
7. The micropore forming method of claim 4 , wherein the speed S (m/s) of the microneedles piercing the skin is set such that 4.8≦S.
8. The micropore forming method of claim 4 , wherein the speed S (m/s) of the microneedles piercing the skin is set such that S≦6.1.
9. The micropore forming method of claim 4 , wherein, after the microneedles have pierced the skin, the spring exerts a force P (Pa) on the skin through the microneedles such that 2.56×10 5 ≦P.