Granted Patent
B2
US 9,308,206 · App. 14/164,459 · Granted Apr 12, 2016
Compositions and methods for treating colon cancer
A61K31/517A61K31/195A61K31/4188A61K31/426A61K31/4747A61K31/502C12Q1/26C12Y101/01021G01N33/5735G01N33/57419C12N15/1137C12N2310/14G01N2500/00
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Abstract
Certain embodiments are directed to methods of treating a pathophysiological state or symptoms thereof resulting from aldose reductase-mediated signaling in a cytotoxic pathway using an aldose reductase specific inhibitor.
Claims (1)
1. A method of inhibiting colon cancer cell proliferation in a subject having colon cancer which consists of administering a pharmacologically effective amount of fidarestat which is a specific inhibitor of aldose reductase to the subject having colon cancer, wherein colon cancer cell proliferation in said subject is inhibited.
Continuity (8)
Continuation In Part
14164459
Provisional Application
60629448
· Nov 19, 2004
Provisional Application
60603725
· Aug 23, 2004