IP Library › Granted Patent US 9,315,458
Granted Patent B2
US 9,315,458 · App. 14/693,342 · Granted Apr 19, 2016

Nitrogen-containing heterocyclic compound

Inventors: Masami Yamada (Kanagawa, JP); Shinkichi Suzuki (Kanagawa, JP); Takahiro Sugimoto (Kanagawa, JP); Minoru Nakamura (Kanagawa, JP); Hiroki Sakamoto (Kanagawa, JP); Makoto Kamata (Kanagawa, JP)
Assignee: Takeda Pharmaceutical Company, Limited
C07D209/46C07D401/10C07D401/14C07D403/04C07D403/10C07D405/14
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Quick Facts
Patent No.
US 9,315,458
App. No.
14/693,342
Granted
Apr 19, 2016
Kind
B2
Abstract

The present invention provides a compound having a cholinergic muscarinic M1 receptor positive allosteric modulator activity and useful as an agent for the prophylaxis or treatment of Alzheimer's disease, schizophrenia, pain, sleep disorder, Parkinson's disease dementia, dementia with Lewy bodies, and the like. The present invention relates to a compound represented by the formula (I) or a salt thereof. wherein each symbol is as described in the specification, or a salt thereof.

Claims (2)

1. 4-Fluoro-2-[(3S,4S)-4-hydroxytetrahydro-2H-pyran-3-yl]-5-methyl-6-[4-(1H-pyrazol-1-yl)benzyl]-2,3-dihydro-1H-isoindol-1-one, or a salt thereof.

2. A medicament comprising 4-Fluoro-2-[(3S,4S)-4-hydroxytetrahydro-2H-pyran-3-yl]-5-methyl-6-[4-(1H-pyrazol-1-yl)benzyl]-2,3-dihydro-1H-isoindol-1-one or a salt thereof, and a pharmaceutically acceptable carrier.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 10, 2015
From: YAMADA, MASAMI; SUZUKI, SHINKICHI; SUGIMOTO, TAKAHIRO; NAKAMURA, MINORU; SAKAMOTO, HIROKI; KAMATA, MAKOTO
To: TAKEDA PHARMACEUTICAL COMPANY LIMITED
Reel/Frame 036291/0730 →
Priority Claims (1)
JP 2014-089585 · Apr 23, 2014 · national
Continuity (1)
Related Publication 20150307451A1 · Oct 29, 2015