IP Library Granted Patent US 9,332,946
Granted Patent B2
US 9,332,946 · App. 13/531,471 · Granted May 10, 2016

Adaptive control of sampling frequency for computed tomography

Inventors: Dominic Heuscher (Park City, UT); Frederic Noo (Midvale, UT)
Assignee: University of Utah Research Foundation
A61B6/032A61B6/06A61B6/405A61B6/481A61B6/507A61B6/5205A61B6/54A61B6/542A61B6/544A61B6/541
View Patent ↗
Loading inventors, assignments & file history…
Monitor This Case
Get email alerts when status or documents change.
Order Certified Copies
Most orders are placed with the USPTO same day — all within 24 business hours.
Order via The Patent Place →
Pre-filled with this patent's details
Quick Facts
Patent No.
US 9,332,946
App. No.
13/531,471
Granted
May 10, 2016
Kind
B2
Abstract

A method of contrast-enhanced computed tomography (CT) imaging can include repeatedly scanning a target region at a frequency during a session, the frequency initially being a first rate. After detecting an increase of the attenuation of radiation by a contrast-enhanced first structure within a target region, the frequency can be increased to a second rate. After detecting a subsequent decrease in the attenuation, the frequency can be decreased to a third rate.

Claims (29)

1. A method of contrast-enhanced computed tomography (CT) imaging, comprising:

(a) repeatedly scanning a target region at a frequency during a session of multiple complete scans, each scan in the session of multiple complete scans comprising emitting x-ray radiation toward the target region from a plurality of angular views, the frequency at which complete scans are performed in the session initially being a first rate;

(b) monitoring, during the session of multiple complete scans, an indicator of attenuation of radiation by a contrast-enhanced first structure within the target region;

(d) after detecting an increase of the attenuation, increasing the frequency at which complete scans are performed in the session to a second rate; and

(e) after detecting a decrease in the attenuation after (d), decreasing the frequency at which complete scans are performed in the session to a third rate.

2. The method of claim 1 , further comprising generating a representation of a relationship between time and radiation attenuation by a second structure within the target region.

3. The method of claim 2 , wherein the radiation attenuation by the second structure with respect to time represents an indicator of vascular perfusion of the second structure.

4. The method of claim 1 , wherein the frequency is increased to the second rate in response to detection of a decrease in a rate at which the attenuation is increasing.

5. The method of claim 4 , further comprising beginning monitoring of the rate of change after detecting an increase of the attenuation to or beyond a threshold.

6. The method of claim 1 , further comprising decreasing the frequency below the third rate in response to detection of a decrease in a rate at which the attenuation is decreasing.

7. The method of claim 6 , wherein decreasing the frequency below the third rate comprises reducing the frequency with each successive scan.

8. The method of claim 1 , wherein the frequency is reduced to the third rate upon a first detection of a decrease in attenuation after (d).

9. The method of claim 1 , wherein the structure comprises at least one of a heart chamber, an aorta, or another blood vessel.

10. The method of claim 1 , further comprising monitoring of a rate of change of the attenuation.

11. A computer-implemented system for controlling contrast-enhanced computed tomography imaging, comprising:

an attenuation monitoring module configured to monitor, during an imaging session comprising multiple complete scans wherein each complete scan comprises emitting x-ray radiation toward a target region from a plurality of angular views, an indicator of attenuation of radiation by a contrast-enhanced structure within the target region;

a scanning-frequency control module configured to (i) increase a frequency at which complete scans are performed in the imaging session from a first rate to a second rate after detection of an increase of the attenuation, and (ii) decrease the frequency to a third rate after detecting a decrease in attenuation after increasing the frequency to the second rate.

12. The computer-implemented system of claim 11 , wherein the scanning-frequency control module is further configured to increase the frequency to the second rate in response to detection of a decrease in a rate at which the attenuation is increasing.

13. The computer-implemented system of claim 11 , wherein the monitoring module is further configured to begin monitoring of the rate of change after detection of compliance of the attenuation with a threshold.

14. The computer-implemented system of claim 11 , further comprising a processing module configured to generate a representation of a relationship between time and radiation attenuation by a second structure within the target region.

15. The computer-implemented system of claim 14 , wherein the radiation attenuation by the second structure with respect to time represents an indicator of vascular perfusion of the second structure.

16. The computer-implemented system of claim 11 , wherein the scanning-frequency control module is further configured to decrease the frequency below the third rate in response to detection of a decrease in a rate at which the attenuation is decreasing.

17. The computer-implemented system of claim 11 , wherein the scanning-frequency control module is further configured to reduce the frequency to the third rate upon a first detection of a decrease in attenuation after an increase to the second rate.

18. The computer-implemented system of claim 11 , wherein the monitoring module is further configured to monitor a rate of change of the attenuation.

19. A method of computed tomography imaging, comprising:

repeatedly scanning a target region at a scan frequency during a session, each scan in the session comprising emitting x-ray radiation into the target region from a plurality of angular views to produce a complete scan;

monitoring, during the session, an indicator of attenuation of radiation by a contrast-enhanced first structure within the target region; and

varying the scan frequency based on the attenuation.

20. The method of claim 19 , wherein x-ray radiation is emitted at a minimum frequency when the attenuation is below a low threshold and at a maximum frequency when then attenuation is above a high threshold.

Assignments (3)
CONFIRMATORY LICENSE Recorded May 18, 2015
From: UNIVERSITY OF UTAH
To: NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT
Reel/Frame 035706/0985 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 7, 2012
From: HEUSCHER, DOMINIC; NOO, FREDERIC
To: UNIVERSITY OF UTAH
Reel/Frame 028915/0487 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 7, 2012
From: UNIVERSITY OF UTAH
To: UNIVERSITY OF UTAH RESEARCH FOUNDATION
Reel/Frame 028915/0553 →
Continuity (1)
Related Publication 20130343512A1 · Dec 26, 2013