Device for forming tissue pieces for tissue array
The invention provides a method for forming tissue pieces which allows stable and accurate winding around a core rod in rolling a sheet-like tissue piece, and a device therefor. In the tissue pieces used as each tissue piece in a tissue array obtained by arranging the tissue pieces on a substrate in an array form, the method for forming a roll-shaped tissue piece 6 obtained by rolling a sheet-like tissue piece 8 is characterized by the facts that the sheet-like tissue piece 8 is produced by slicing a tissue block 5 obtained by embedding the tissues with an embedding medium, the sheet-like tissue piece 8 is placed on a mounting block 12 , peeling means 13 which easily enables peeling of the tissue piece 8 from the mounting block 12 is applied between the mounting block 12 and the tissue piece 8 , and the tissue piece 8 is wound around a core rod 11 while heating the tissue piece 8 on the mounting block 12.
1. A device for forming tissue pieces for a tissue array comprising:
a mounting block comprising an upper face on which a previously sliced sheet-like tissue piece is operable to be placed, the previously sliced tissue piece made by slicing a tissue block of a tissue in an embedding medium;
a means for enabling peeling off of the tissue piece from the mounting block, said peeling means being provided on the upper face of the mounting block;
a first heating unit operable to heat the sheet-like tissue piece placed on the mounting block;
a core rod-attaching part operable to attach a core rod for winding the sheet-like tissue piece, being provided above the upper face of the mounting block;
a motor coupled to the core rod-attaching part and operable to rotate a core rod attached to the core rod-attaching part around the shaft core of the core rod;
a means for horizontally moving the core rod-attaching part relative to the upper face of the mounting block;
a control unit which controls the motor and the horizontal moving means so that the core rod is horizontally moved by the horizontal moving means while rotating by the motor, such that a sheet-like tissue piece placed on the upper face of the mounting block is wound around the core rod into a cylindrical form;
a second heating unit operable to heat a roll-shaped tissue piece rolled around the core rod in order to adapt it;
a cooling unit operable to cool a roll-shaped tissue piece heated by the second heating unit; and
a cutting unit operable to cut a roll-shaped tissue piece and the core rod cooled by the cooling unit, to form a cylindrical body of a predetermined length.
2. The device according to claim 1 , wherein the peeling means comprises an embedding medium having a melting point lower than that the embedding medium of the sheet-like tissue piece.
3. The device according to claim 1 , wherein the embedding medium is paraffin.
4. The device according to claim 1 , wherein the peeling means comprises an upper face of the mounting block that is roughened.
5. The device according to claim 1 , further comprising a plate operable to be positioned and detachable from the upper face of the mounting block, and wherein the peeling means is applied to an upper face of the plate.
6. The device according to claim 1 , the device including means that press the core rod in a direction of the sheet-like tissue piece when the sheet-like tissue piece is wound around the core rod attached to said core rod-attaching part, and which can move following movement of the core rod by said horizontal moving means.
7. The device according to claim 1 , wherein the mounting block slopes in a direction gradually being spaced apart from the core rod toward a moving direction of the core rod.
8. The device according to claim 1 , wherein the core rod-attaching part is provided so that it can move in a direction gradually being spaced apart from the sheet-like tissue piece toward the moving direction of the core rod.
9. The device according to claim 1 , wherein when the sheet-like tissue piece is wound around the core rod attached to said core rod-attaching part, the control unit performs control so that an amount of movement by the horizontal moving means is gradually increased and a rotation speed by the motor is gradually lowered.
10. The device according to claim 1 , wherein the embedding medium is coated on the surface of said core rod.