IP Library Granted Patent US 9,340,576
Granted Patent B2
US 9,340,576 · App. 13/909,712 · Granted May 17, 2016

Methods of treating depression and other related diseases

Inventor: Joseph Moskal (Evanston, IL)
Assignee: Northwestern University
C07K5/1013A61K38/07A61K45/06C07K5/06139C07K5/081C07K5/0821
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Quick Facts
Patent No.
US 9,340,576
App. No.
13/909,712
Granted
May 17, 2016
Kind
B2
Abstract

The invention relates to methods for treating depression, anxiety, and other related diseases by administering a peptide NMDAR partial agonist.

Claims (11)

1. A method for treating dysthymic disorder in a patient in need thereof, comprising administering to said patient a 1 mg/kg to about 10 mg/kg dose of a compound represented by:

or pharmaceutically acceptable salts, homologs, or hydrates thereof.

2. The method of claim 1 , comprising administering the composition every week or every two weeks to said patient.

3. The method of claim 1 , wherein administration of a single dose is effective for up to 4 days.

4. The method of claim 1 , further comprising administering another antidepressant drug.

5. he method of claim 2 , further comprising administering another antidepressant drug.

6. A method for treating dysthymic disorder in a patient in need thereof, comprising administering to said patient a pharmaceutically acceptable composition comprising:

a 1 mg/kg to about 10 mg/kg dose of a compound represented by:

 and

an excipient.

7. A method for treating dysthymic disorder in a patient in need thereof, comprising administering to said patient a 1 mg/kg to about 10 mg/kg dose of a compound represented by:

Assignments (3)
SECURITY INTEREST Recorded Dec 18, 2024
From: GATE NEUROSCIENCES, INC.
To: INNOVIVA TRC HOLDINGS LLC
Reel/Frame 069742/0846 →
SECURITY INTEREST Recorded Nov 6, 2023
From: GATE NEUROSCIENCES, INC.
To: INNOVIVA TRC HOLDINGS LLC
Reel/Frame 065473/0327 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 22, 2013
From: MOSKAL, JOSEPH
To: NORTHWESTERN UNIVERSITY
Reel/Frame 031062/0182 →
Continuity (7)
Continuation 13608556 · Sep 10, 2012
Continuation 13440368 · Apr 5, 2012
Continuation In Part PCTUS2010051415 · Oct 5, 2010
Provisional Application 61248650 · Oct 5, 2009
Provisional Application 61471942 · Apr 5, 2011
Provisional Application 61507252 · Jul 13, 2011
Related Publication 20130288975A1 · Oct 31, 2013