Optimal pacing configuration via ventricular conduction delays
An exemplary method for optimizing pacing configuration includes providing distances between electrodes of a series of three or more ventricular electrodes associated with a ventricle; selecting a ventricular electrode from the series; delivering energy to the ventricle via the selected ventricular electrode, the energy sufficient to cause an evoked response; acquiring signals of cardiac electrical activity associated with the evoked response via non-selected ventricular electrodes of the series; based on signals of cardiac electrical activity acquired via the non-selected ventricular electrodes and the distances, determining conduction velocities; based on the conduction velocities, deciding if the selected ventricular electrode is an optimal electrode for delivery of a cardiac pacing therapy; and, if the selected ventricular electrode comprises an optimal electrode for delivery of the cardiac pacing therapy, calling for delivery of the cardiac pacing therapy using the selected ventricular electrode. Various other methods, devices, systems, etc., are also disclosed.
1. A method comprising:
providing a plurality of distances between electrodes of a series of three or more ventricular electrodes associated with a first ventricle;
selecting a ventricular electrode from the series;
delivering energy to the first ventricle via the selected ventricular electrode, the energy sufficient to cause an evoked response;
acquiring signals of cardiac electrical activity associated with the evoked response via a plurality of the non-selected ventricular electrodes of the series;
based on signals of cardiac electrical activity acquired via the plurality of non-selected ventricular electrodes and the plurality of distances, determining conduction velocities;
based on the conduction velocities, deciding if the selected ventricular electrode comprises an optimal electrode for delivery of a cardiac pacing therapy; and
where the selected ventricular electrode comprises an optimal electrode for delivery of the cardiac pacing therapy, calling for delivery of the cardiac pacing therapy using the selected ventricular electrode.
2. The method of claim 1 wherein if the selected ventricular electrode does not comprise an optimal electrode for delivery of the cardiac pacing therapy, repeating the selecting to select a different ventricular electrode from the series and repeating the delivering, the acquiring, the determining and the deciding for the selected, different ventricular electrode.
3. The method of claim 1 wherein the determining conduction velocities comprises, for each of the non-selected ventricular electrodes, dividing the distance between the non-selected ventricular electrode and the selected ventricular electrode by an intra-ventricular conduction delay.
4. The method of claim 3 wherein the intra-ventricular conduction delay for each of the non-selected electrodes comprises a difference between a delivery time for the delivered energy and an evoked response time based on signals of cardiac electrical activity acquired via the non-selected electrodes.
5. The method of claim 1 further comprising:
acquiring signals of cardiac electrical activity via the selected ventricular electrode; and
based on signals of cardiac electrical activity acquired via the selected ventricular electrode, determining a pacing latency.
6. The method of claim 1 further comprising acquiring signals of cardiac electrical activity associated with the evoked response via a ventricular electrode associated with a second ventricle.
7. The method of claim 1 further comprising acquiring signals of cardiac electrical activity via an atrial electrode.
8. The method of claim 1 further comprising determining a sum of the conduction velocities, and wherein the deciding comprises deciding based on the sum of the conduction velocities.
9. The method of claim 1 further comprising determining a standard deviation of the conduction velocities, and wherein the deciding comprises deciding based on the standard deviation of the conduction velocities.
10. The method of claim 1 wherein the first ventricle comprises a left ventricle.
11. The method of claim 1 further comprising analyzing the signals of cardiac electrical activity acquired via the non-selected ventricular electrodes for indicia of functional conduction block.