IP Library › Granted Patent US 9,399,219
Granted Patent B2
US 9,399,219 · App. 12/697,184 · Granted Jul 26, 2016

Thermal Array

Inventor: Frank Leo Spangler (Saint George, UT)
B01L7/5255B01L2300/0809B01L2300/1805B01L2300/1822B01L2300/1827B01L2300/1883
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Quick Facts
Patent No.
US 9,399,219
App. No.
12/697,184
Granted
Jul 26, 2016
Kind
B2
Abstract

Traditional thermocyclers are heating devices that change sample temperatures by adding heat energy into a sample block that is usually a large metal block and then extracting that heat energy out of the block in a process called ramping the temperature. Presented herein is a technology that eliminates the large mass sample block and ramping temperatures in a sample block and thus in a sample vessel. This design called a Thermal Array requires a fraction of the energy used to process a sample. In addition, the array allows a much smaller thermal cycler to be designed leading to portability of a device. This technology is designed to allow optimal polymerase chain reactions to be executed.

Claims (7)

1. A portable thermal-cycling device, comprising:

a first heating element surrounded by insulation on five sides and embedded in a cooling block;

a second heating element surrounded by insulation on five sides and embedded in the cooling block; and

wherein the first and second heating elements are separated by a portion of the cooling block, wherein the cooling block comprises at least one Peltier element.

2. A portable thermal-cycling device, comprising:

two arrays opposite each other and forming a sample channel, each array comprising two or more heating elements surrounded by insulation on five sides and embedded in a cooling block; and

a reaction vessel within the sample channel.

Continuity (2)
Provisional Application 61152546 · Feb 13, 2009
Related Publication 20100210006A1 · Aug 19, 2010