Dissolvable films containing high concentrations of nonionic surfactants such as polysorbates to enhance high solid loadings
An oral care composition and method are described in which the composition includes a film or a plurality of film fragments entrained in a carrier. The film or plurality of film fragments comprises a relatively high concentration of nonionic surfactants. The composition and methods provide benefits including higher active material loading in the film formula for improved efficacy, and a reduced amount of film needed in a product, which at the same time delivering comparable or improved efficacy with lower loading of the film in the composition.
1. An oral care composition comprising a film entrained in a carrier,
wherein the film comprises
a nonionic surfactant in an amount from 5% by weight of the film to 20% by weight of the film and
a solid active ingredient in an amount from 30% by weight of the film to 55% by weight of the film, and
wherein the film is present in an amount of from 0.1% to 5.0% by weight of the total weight of the composition.
2. The oral care composition of claim 1 , wherein the composition is in the form of a dentifrice.
3. The oral care composition of claim 1 , wherein the nonionic surfactant comprises a polysorbate.
4. The oral care composition of claim 3 , wherein the polysorbate is selected from the group consisting of polysorbate 20, polysorbate 40, polysorbate 60, polysorbate 80, and combinations thereof.
5. The oral care composition of claim 4 , wherein the polysorbate is polysorbate 80.
6. The oral care composition of claim 1 , wherein the solid active ingredient comprises a therapeutic active.
7. The oral care composition of claim 6 , wherein the therapeutic active is present in the film in an amount of from 30% by weight of the film to 55% by weight of the film.
8. The oral care composition of claim 1 , wherein the film is present in an amount of from 0.25% to 3.0% by weight of the total weight of the composition.
9. The oral care composition of claim 8 , wherein the film is present in an amount of from 0.5% to 2.0% by weight of the total weight of the composition.
10. A method of making an oral care composition comprising a film entrained in a carrier wherein the film comprises a nonionic surfactant in an amount from 5% by weight of the film to 20% by weight of the film and a solid active ingredient in an amount from 30% by weight of the film to 55% by weight of the film, and wherein the film is present in an amount of from 0.1% to 5.0% by weight of the total weight of the composition,
the method comprising:
(a) providing the carrier;
(b) adding lamellar fragments of the film comprising the nonionic surfactant in an amount from 5% by weight of the film to 20% by weight of the film and the solid active ingredient in an amount from 30% by weight of the film to 55% by weight of the film; and
(c) homogenizing the mixture.
11. The method of claim 10 , wherein the nonionic surfactant is polysorbate 80.
12. The method of claim 10 , wherein the solid active ingredient comprises a therapeutic active.
13. The method of claim 12 , wherein the therapeutic active is present in the film in an amount of from 30% by weight of the film to 55% by weight of the film.
14. A method for administering an active to a human or animal subject in need thereof comprising topically applying to the subject an oral care composition comprising a film, wherein the film comprises a nonionic surfactant in an amount from 5% by weight of the film to 20% by weight of the film and a solid active ingredient in an amount from 30% by weight of the film to 55% by weight of the film, and wherein the film is present in an amount of from 0.1% to 5.0% by weight of the total weight of the composition.
15. The method of claim 14 , further comprising disrupting the film after the topical application.
16. The method of claim 14 , wherein the nonionic surfactant is polysorbate 80.
17. The method of claim 14 , wherein the solid active ingredient comprises a therapeutic active.
18. The method of claim 17 , wherein the therapeutic active is present in the film in an amount of from 30% by weight of the film to 55% by weight of the film.