IP Library › Granted Patent US 9,427,173
Granted Patent B2
US 9,427,173 · App. 12/118,628 · Granted Aug 30, 2016

Determining mechanical force on aneurysms from a fluid dynamic model driven by vessel blood flow information

Inventors: Saad Ahmed Sirohey (Pewaukee, WI); Paul E. Licato (Milwaukee, WI); Gopal B. Avinash (Menomonee Falls, WI); Tamanna N. Bembenek (Milwaukee, WI)
Assignee: General Electric Company
A61B5/1075A61B5/02007A61B6/032A61B6/481A61B6/504G06F19/321G06F19/345G06F19/3437G06T7/0012G06T15/08G06T2207/10081G06T2207/10088G06T2207/30101
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Quick Facts
Patent No.
US 9,427,173
App. No.
12/118,628
Filed
May 9, 2008
Granted
Aug 30, 2016
Kind
B2
Art Unit
3777
USPC
600/431
Abstract

Systems, methods and apparatus are provided through which in some implementations changes in an aneurysm in a patient over time are identified by determining temporal differences between segmented aneurysms in a plurality of longitudinal exams and visually presenting the temporal differences.

Claims (59)

1. A method to image a patient, the method comprising:

accessing four-dimensional image data that tracks a flow of a previously injected contrast agent through a vasculature;

determining vessel flow information of the vasculature;

determining mechanical force attributes on a wall of an aneurysm from the vessel flow information using a fluid dynamics model wherein the mechanical force attributes vary in proportion to velocity of fluid in the vasculature in a direction perpendicular to a plane of shear in the vasculature;

generating a three-dimensional image of the vasculature using the four-dimensional image data; and

visually presenting the determined mechanical force attributes in the three-dimensional image using visual cues to indicate degree of mechanical force attributes.

2. The method of claim 1 , wherein the fluid dynamics model further comprises:

a Navier-Stokes fluid dynamics model.

3. The method of claim 1 , wherein the accessing further comprises:

accessing four-dimensional data that tracks contrast flow through a vasculature.

4. The method of claim 1 , wherein the determining vessel flow information further comprises:

detecting a velocity of contrast uptake in a vessel; and

detecting a cross-sectional area of the vessel.

5. The method of claim 1 , wherein the determining vessel flow information further comprises:

identifying two points on a vessel being a distance apart from each other;

determining a time for each of the two points of which flow in the vessel reaches a steady state contrast enhanced value; and

determining the velocity by dividing the distance by the difference of the two times.

6. The method of claim 1 , further comprising:

generating a report of the determined mechanical force attributes; and

storing the report.

7. The method of claim 1 , further comprising:

providing treatment based on the determined mechanical force attributes.

8. A non-transitory computer-accessible medium having executable instructions to image a patient, the executable instructions capable of directing a processor to perform:

determining mechanical force attributes on a wall of an aneurysm using a fluid dynamics model; and

visually presenting the determined mechanical force attributes in three-dimensional rendition of the volumetric data using visual cues to indicate degree of mechanical force attributes.

9. The non-transitory computer-accessible medium of claim 8 , wherein the fluid dynamics model further comprises:

a Navier-Stokes fluid dynamics model.

10. The non-transitory computer-accessible medium of claim 8 ,

wherein the mechanical force attributes further comprises:

linearly proportional to velocity of fluid in a proximity to a location in a direction perpendicular to a plane of shear in the location.

11. The non-transitory computer-accessible medium of claim 8 , the medium further comprising executable instructions capable of directing the processor to perform:

accessing four-dimensional image data that describes a contrast flow, of a previously injected contrast agent, through a vasculature; and

determining vessel flow information.

12. The non-transitory computer-accessible medium of claim 11 , wherein the executable instructions capable of directing the processor to perform the accessing further comprise executable instructions capable of directing the processor to perform:

accessing four-dimensional image data that describes contrast flow through a vasculature.

13. The non-transitory computer-accessible medium of claim 11 , wherein the executable instructions capable of directing the processor to perform the determining vessel flow information further comprise executable instructions capable of directing the processor to perform:

detecting a velocity of contrast uptake in a vessel; and

detecting a cross-sectional area of the vessel.

14. The non-transitory computer-accessible medium of claim 13 , wherein the executable instructions capable of directing the processor to perform the determining vessel flow information further comprise executable instructions capable of directing the processor to perform:

identifying two points on a vessel being a distance apart from each other;

determining a time for each of the two points of which flow in the vessel reaches a steady state contrast enhanced value; and

determining the velocity by dividing the distance by the difference of the two times.

15. The non-transitory computer-accessible medium of claim 8 further comprising executable instructions capable of directing the processor to perform:

generating a report of the determined mechanical force attributes; and

storing the report.

16. The non-transitory computer-accessible medium of claim 8 further comprising executable instructions capable of directing the processor to perform:

providing treatment based on the determined mechanical force attributes.

17. A medical imaging system comprising:

a processor;

a storage device coupled to the processor;

software apparatus operable on the processor comprising:

a fluids dynamics model;

a vessel flow analyzer operable to determine vessel flow data of a vasculature represented in four-dimensional image data; and

a mechanical force analyzer that is operable to determine a mechanical force attributes on a wall of an aneurysm from the vessel flow data using the fluid dynamics model wherein the mechanical force attributes varies in proportion to a velocity of a fluid in the vasculature in a direction perpendicular to a plane of shear in the vasculature;

wherein an apparatus operable to visually display the mechanical force attributes in three-dimensional rendition of the volumetric data using visual cues to indicate a degree of mechanical force attributes.

18. The medical imaging system of claim 17 , wherein the fluid dynamics model further comprises:

a Navier-Stokes fluid dynamics model.

19. The medical imaging system of claim 17 , wherein the four-dimensional image data further comprises:

four-dimensional image data.

Assignments (2)
NUNC PRO TUNC ASSIGNMENT Recorded May 8, 2025
From: GENERAL ELECTRIC COMPANY
To: GE PRECISION HEALTHCARE LLC
Reel/Frame 071225/0218 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded May 10, 2008
From: AVINASH, GOPAL B.; SIROHEY, SAAD AHMED; LICATO, PAUL E.; BEMBENEK, TAMANNA N.
To: GENERAL ELECTRIC COMPANY
Reel/Frame 020931/0293 →
Continuity (1)
Related Publication 20090281423A1 · Nov 12, 2009