IP Library Granted Patent US 9,452,036
Granted Patent B2
US 9,452,036 · App. 13/516,678 · Granted Sep 27, 2016

Dental ultrasonic drug delivery system and dental ultrasonic drug delivery method

Inventors: Misako Nakashima (Obu, JP); Katsuro Tachibana (Fukuoka, JP)
Assignees: National Center for Geriatrics and Gerontology; Fukuoka University
A61C17/0202A61C17/20A61C5/02
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Quick Facts
Patent No.
US 9,452,036
App. No.
13/516,678
Granted
Sep 27, 2016
Kind
B2
Abstract

A dental ultrasonic drug delivery system capable of accurately cleaning the inside of root canals and killing bacteria in dentin tubules is provided. The dental ultrasonic drug delivery system delivers a drug to a target using an ultrasonic delivery device 800 . The drug is delivered in a mixed state with nanobubbles. A dental therapeutic probe for applying ultrasound is attached to the ultrasonic delivery device 800 . The dental therapeutic probe is selected from: (1) a root canal insertion probe 100 which is configured to be inserted into a root canal and causes ultrasound to propagate in the root canal; (2) a dental caries therapeutic probe which causes ultrasound to propagate in a dental caries portion; (3) a periodontal disease therapeutic probe which applies ultrasound to a periodontal disease portion; and (4) a hyperesthesia therapeutic probe which applies ultrasound to hyperesthesia portion.

Claims (11)

1. A dental ultrasonic drug delivery system comprising:

a drug mixed with nanobubbles;

a dental therapeutic probe; and

an ultrasonic transducer configured to deliver ultrasonic energy from the dental therapeutic probe at a frequency in the range from 800 KHz to 2 MHz, both inclusive, wherein

the dental ultrasonic drug delivery system delivers the drug to a target,

the dental therapeutic probe includes a probe body and an introduction probe attached to the probe body and configured to be used for introducing the drug to the target,

the dental therapeutic probe is a hyperesthesia therapeutic probe, which includes a wedge-shaped defect portion pad formed by modeling an impression of a wedge-shaped defect portion of tooth enamel, the ultrasonic transducer configured to generate the ultrasonic energy, and a fluid path, which is located between the ultrasonic transducer and the wedge-shaped defect portion pad, and through which a fluid flows, the hyperesthesia therapeutic probe being configured to apply the ultrasonic energy to a hyperesthesia portion, and

the wedge-shaped defect portion pad comprises at least one depressed portion of which a cross-section perpendicular to a root canal direction is generally a semicircular recess.

2. The dental ultrasonic drug delivery system of claim 1 , wherein the target is a wedge-shaped defect portion of enamel.

3. The dental ultrasonic drug delivery system of claim 1 , wherein each of the nanobubbles has a diameter of 10 nm to 500 nm, both inclusive.

4. The dental ultrasonic drug delivery system of claim 1 , wherein the drug includes at least one of oxalic acid, a diamine silver fluoride product, copal resin, sodium fluoride, zinc chloride, a water-soluble aluminum compound, water soluble calcium, BMPs, or bFGF.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 18, 2012
From: NAKASHIMA, MISAKO; TACHIBANA, KATSURO
To: NATIONAL CENTER FOR GERIATRICS AND GERONTOLOGY; FUKUOKA UNIVERSITY
Reel/Frame 028392/0718 →
Priority Claims (1)
JP 2009-285068 · Dec 16, 2009 · national
Continuity (1)
Related Publication 20120270177A1 · Oct 25, 2012