IP Library › Granted Patent US 9,469,646
Granted Patent B2
US 9,469,646 · App. 14/839,273 · Granted Oct 18, 2016

Modulators of methyl modifying enzymes, compositions and uses thereof

Inventors: Brian K. Albrecht (Cambridge, MA); James Edmund Audia (Cambridge, MA); Les A. Dakin (Natick, MA); Victor S. Gehling (Somerville, MA); Jean-Christophe Harmange (Andover, MA); Christopher G. Nasveschuk (Stoneham, MA); Rishi G. Vaswani (Lexington, MA)
Assignee: Constellation Pharmaceuticals, Inc.
C07D487/04C07D401/12C07D401/14C07D405/14C07D409/06C07D417/04C07D417/14C07D471/04
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Quick Facts
Patent No.
US 9,469,646
App. No.
14/839,273
Granted
Oct 18, 2016
Kind
B2
Abstract

Agents for modulating methyl modifying enzymes, compositions and uses thereof are provided herein.

Claims (8)

1. A compound of the formula:

or a pharmaceutically acceptable salt thereof.

2. The compound of claim 1 , wherein the compound is of the formula:

or a pharmaceutically acceptable salt thereof.

3. A pharmaceutical composition comprising a compound of the formula:

or a pharmaceutically acceptable salt thereof; and a pharmaceutically acceptable carrier.

4. The pharmaceutical composition of claim 3 , wherein the compound is of the formula:

or a pharmaceutically acceptable salt thereof.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 9, 2015
From: ALBRECHT, BRIAN K.; AUDIA, JAMES EDMUND; COOK, ANDREW; DAKIN, LES A.; DUPLESSIS, MARTIN; GEHLING, VICTOR S.; HARMANGE, JEAN-CHRISTOPHE; NASVESCHUK, CHRISTOPHER G.; VASWANI, RISHI G.
To: CONSTELLATION PHARMACEUTICALS, INC.
Reel/Frame 036521/0745 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 8, 2015
From: ALBRECHT, BRIAN K.; AUDIA, JAMES EDMUND; COOK, ANDREW; DAKIN, LES A.; DUPLESSIS, MARTIN; GEHLING, VICTOR S.; HARMANGE, JEAN-CHRISTOPHE; NASVESCHUK, CHRISTOPHER G.; VASWANI, RISHI G.
To: CONSTELLATION PHARMACEUTICALS, INC.
Reel/Frame 036511/0145 →
Priority Claims (1)
WO PCT/US2013/025639 · Feb 11, 2013 · international
Continuity (2)
Continuation 14766632
Related Publication 20150368229A1 · Dec 24, 2015