Beta-lactam compounds for treating diabetes
Compositions and methods comprising ampicillin or salts and derivative thereof for the treatment of delaying the onset of type I diabetes are provided.
1. A method for treating type I diabetes in a subject in need thereof, the method comprising administering to the subject a pharmaceutical composition comprising ampicillin or a salt thereof, thereby treating type I diabetes in said subject.
2. The method of claim 1 , wherein the administered pharmaceutical composition comprises a sub-antibacterial dose of ampicillin.
3. The method of claim 1 , wherein the pharmaceutical composition comprising ampicillin is administered in a sub-antibacterial treatment regime.
4. The method of claim 1 , wherein the ampicillin is conjugated to a protein, and wherein the ampicillin-protein conjugate is devoid of antibacterial activity.
5. The method of claim 4 , wherein the ampicillin is conjugated to albumin.
6. The method of claim 5 , wherein the albumin is human serum albumin.
7. The method of claim 1 , wherein the subject is human.
8. The method of claim 1 , wherein the subject is a non-human mammal.
9. The method of claim 1 , wherein the subject is newly diagnosed with type I diabetes.
10. The method of claim 1 , wherein the subject is at risk of developing type I diabetes.