IP Library › Granted Patent US 9,499,539
Granted Patent B2
US 9,499,539 · App. 14/440,796 · Granted Nov 22, 2016

Cyclic sulfonamide containing derivatives as inhibitors of hedgehog signaling pathway

Inventors: Chunlin Tao (Newport Coast, CA); Chengzhi Yu (San Diego, CA); Forrest Arp (Irvine, CA); Paul Weingarten (Anaheim, CA); Patrick Soon-Shiong (Los Angeles, CA)
Assignee: NantBioScience, Inc.
C07D471/04C07D275/02C07D279/02C07D291/06C07D417/12C07D419/12
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Quick Facts
Patent No.
US 9,499,539
App. No.
14/440,796
Granted
Nov 22, 2016
Kind
B2
Abstract

The invention relates generally to the creation and use of cyclic sulfonamide containing derivatives to inhibit the hedgehog signaling pathway and to the use of those compounds for the treatment of hyperproliferative diseases and angiogenesis mediated diseases.

Claims (1)

1. A compound with the structure:

Continuity (3)
Provisional Application 61852112 · Mar 15, 2013
Provisional Application 61722490 · Nov 5, 2012
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