IP Library Granted Patent US 9,506,846
Granted Patent B2
US 9,506,846 · App. 13/962,202 · Granted Nov 29, 2016

High definition nanomaterials

Inventors: Michael Rubner (Westford, MA); Brian L. Wardle (Lexington, MA); Robert E. Cohen (Jamaica Plain, MA); Mehmet Toner (Wellesley, MA); Fabio Fachin (Cambridge, MA)
Assignees: Massachusetts Institute of Technology; The General Hospital Corporation
G01N1/34B01L3/502707B01L3/502753B01L2300/0636B01L2300/0877B01L2300/0896B01L2400/086G01N2001/4088
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Quick Facts
Patent No.
US 9,506,846
App. No.
13/962,202
Granted
Nov 29, 2016
Kind
B2
Abstract

A microfluidic device for manipulating particles can include a substrate and one or more obstacles, each obstacle comprising a plurality of aligned nanostructures including a plurality of nanoparticles or a plurality of polymer layers, or a combination thereof. The obstacle on a substrate can be forests with intra-carbon nanotube spacing ranging between 5-100 nm for isolation of particles such as very small viruses and proteins.

Claims (8)

1. A fluidic device for manipulating particles comprising:

a substrate that defines a fluid path; and

one or more obstacles, each obstacle comprising a plurality of aligned nanostructures, wherein the nanostructures are coated with one or more layers of a plurality of nanoparticles and a plurality of polymer layers, wherein nanostructures form an outer surface of an obstacle in the fluid path; wherein the one or more obstacles are fixedly arranged within the fluid path such that some expected paths within the fluid path pass around the outer surface of an obstacle and some expected paths within the fluid path pass through the outer surface of an obstacle and into a network of spaces within the obstacle between the nanostructures.

2. The fluidic device of claim 1 , wherein the nanostructures include a plurality of nanoparticles.

3. The fluidic device of claim 1 , wherein the nanostructures include a plurality of polymer layers.

4. The fluidic device of claim 1 , wherein a distance between adjacent nanostructures is less than 100 nm.

5. The fluidic device of claim 1 , wherein a distance between adjacent nanostructures is less than 10 nm.

6. The fluidic device of claim 1 , wherein the nanostructure is a carbon nanotube.

Assignments (3)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 21, 2016
From: TONER, MEHMET
To: THE GENERAL HOSPITAL CORPORATION
Reel/Frame 040087/0341 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 21, 2016
From: COHEN, ROBERT E.; FACHIN, FABIO; WARDLE, BRIAN LEE; RUBNER, MICHAEL F.
To: MASSACHUSETTS INSTITUTE OF TECHNOLOGY
Reel/Frame 040087/0559 →
CONFIRMATORY LICENSE Recorded Aug 1, 2014
From: MASSACHUSETTS INSTITUTE OF TECHNOLOGY
To: NATIONAL SCIENCE FOUNDATION
Reel/Frame 033460/0501 →
Continuity (2)
Provisional Application 61680770 · Aug 8, 2012
Related Publication 20140079601A1 · Mar 20, 2014