Biomarkers for prediction, diagnosis, and monitoring of Alzheimer's disease
View Patent ↗A method for the risk detection, early diagnosis, prognosis, and monitoring of Alzheimer's disease in an individual by measuring the amount of specific biomarkers present in a bodily fluid and comparing them to a reference level of biomarkers in a sample from a healthy person, a person previously diagnosed with Alzheimer's disease, or an earlier sample from the individual of interest.
1. A kit for determining whether a patient has Alzheimer's disease comprising a solid support on which a plurality of agents have been affixed which in combination bind to Aβ40, Aβ42, alpha amylase, and at least one or more additional biomarkers selected from the group of biomarkers consisting of IGF-I, IGF-II, IL-1 beta, TNF-alpha, wherein each agent binds to a different single biomarker.
2. The kit of claim 1 , further comprising instructions to take a saliva sample from the patient in a similar manner.
3. The kit of claim 1 , further comprising instructions to take a saliva sample from the patient within a same time of day window.
4. The kit of claim 1 , further comprising instructions to take a saliva sample from the patient in a similar manner and within a same time of day window.