Granted Patent B2

US 9,545,457 · App. 14/188,598 · Granted Jan 17, 2017

Inventors: Poh K. Hui (Wellesley Hills, MA); John E. Bishop (Groton, MA); Eleodoro S. Madrigal, Jr. (Westford, MA)

Assignee: Lantheus Medical Imaging, Inc.

A61K49/226A61B8/00A61K9/1277A61K47/10A61K49/227A61K47/24

Abstract

Claims (8)

1. A method comprising

using an ultrasound contrast agent to enhance contrast in an echocardiographic ultrasound image of a subject, wherein the ultrasound contrast agent comprises

1,2-dipalmitoyl-sn-glycero-3-phosphotidic acid, mono sodium salt (DPPA), 1,2-dipalmitoyl-sn-glycero-3-phosphatidylcholine (DPPC), and N-(methoxypolyethylene glycol 5000 carbamoyl)-1,2-dipalmitoyl-sn-glycero-3-phosphatidylethanolamine, mono sodium salt (MPEG5000-DPPE), present in a mole ratio of 10% to 82% to 8%, and in an amount of about 0.75 mg/mL;

sodium chloride;

glycerin, present in an amount of about 0.1 mL/mL;

propylene glycol, present in an amount of about 0.1 mL/mL;

water, and

perfluoropropane.

Assignments (8)

Continuity (6)