Containers for pharmaceuticals, particularly for use in radioisotope generators
A radioisotope generator system can include a column assembly having a column, an inlet arm, an outlet arm. The column can contain packing material that binds a radioisotope. In addition, the column may define a notch between an open area and a stopper receptacle area in which an opening of the outlet arm is positioned. In some examples, the system includes a Luer lock connection between the outlet arm and a connector tubing. The Luer lock connection can include a male Luer cap and a female Luer cap each comprising tabs configured to line up with or overlap each other so as to indicate when the caps are sufficiently tightened together so as to form a non-leaking lock.
1. A system comprising:
a radioisotope generator column assembly that includes a hollow column, an inlet arm attached substantially perpendicularly to the hollow column, and an outlet arm attached at an acute angle with respect to the hollow column, wherein the column has a packing area containing a packing material binding a radioisotope, a stopper receptacle area, and an open area positioned between the packing area and the stopper receptacle area, and wherein the column defines an internal notch between the open area and the stopper receptacle area and an opening of the outlet arm is positioned in the internal notch, wherein the outlet arm does not protrude into a hollow portion of the column and the internal notch is provided in the hollow column at a point where the outlet arm intersects the hollow column;
a connector tubing; and
a Luer lock connection attached to the outlet arm and the connector tubing, wherein the Luer lock connection comprises a female Luer cap and a male Luer cap, wherein one of the female and male Luer caps contain a flange and the other of the female and male Luer caps contains threads, the female Luer cap and the male Luer cap being configured so that the flange and threads cooperate with each other in such a way that the female Luer cap and male Luer cap can be screwed together, wherein the male Luer cap and the female Luer cap each comprises one or more tabs, and wherein the one or more tabs on the male Luer cap are configured to at least one of line up with or overlap the one or more tabs on the female Luer cap so as to indicate when the male Luer cap and the female Luer cap are sufficiently tightened together so as to form a non-leaking lock.
2. The system of claim 1 , wherein each of the one or more tabs on the male Luer cap are configured to line up with a corresponding tab of the one or more tabs on the female Luer cap when the male Luer cap and the female Luer cap are sufficiently tightened.
3. The system of claim 1 , wherein each of the one or more tabs on the male Luer cap are configured to overlap with a corresponding tab of the one or more tabs on the female Luer cap when the male Luer cap and the female Luer cap are sufficiently tightened.
4. The system of claim 3 , wherein each of the one or more tabs on the male Luer cap are configured to click past a corresponding tab of the one or more tabs on the female Luer cap when positioning the one or more tabs on the male Luer cap in an overlapping arrangement with the corresponding tab of the one or more tabs on the female Luer cap.
5. The system of claim 1 , wherein the male and female Luer caps each have two tabs.
6. The system of claim 1 , wherein the female Luer cap comprises the flange and the male Luer cap comprises the threads.
7. The system of claim 1 , wherein the flange is configured to engage and mate with the threads.
8. The system of claim 1 , wherein the outlet arm extends from a proximal end to a distal end, the distal end of the outlet arm terminates in the female Luer cap, and the connector tubing comprises the male Luer cap.
9. The system of claim 8 , wherein the connector tubing and the Luer lock connection are fabricated from radiation resistant polyvinyl chloride.