IP Library › Granted Patent US 9,574,175
Granted Patent B2
US 9,574,175 · App. 13/225,911 · Granted Feb 21, 2017

Endometrial polyp stem cell

Inventor: Dah-Ching Ding (Hualien, TW)
Assignee: Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation
C12N5/0618C12N5/0652C12N5/0682C12N2506/243
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Quick Facts
Patent No.
US 9,574,175
App. No.
13/225,911
Granted
Feb 21, 2017
Kind
B2
Abstract

An endometrial polyp stem cell is disclosed in the present invention. The endometrial polyp stem cell is isolated from an endometrial polyp tissue, expresses vimentin, CD13, CD29, CD44, and CD90, and has no expression of CD1q, CD3, CD34, and CD45.

Claims (4)

1. A formulation comprising: an endometrial polyp stem cell, which is isolated from an endometrial polyp tissue wherein the endometrial polyp stem cell expresses vimentin, CD13, CD29, CD44, and CD90, and has TERT expression statistically significantly lower than a human embryonic stem cell or a cancer cell, and an osteogenic medium comprising dexamethasone, β-glycerol phosphate, and ascorbate.

2. The formulation of claim 1 , wherein the endometrial polyp stem cell has no expression of CD3, CD34, and CD45.

3. The formulation of claim 1 , wherein the endometrial polyp tissue is obtained from endometrium of a hysterectomy specimen.

4. The formulation of claim 1 , wherein the endometrial polyp stem cell has clonogenicity.

Assignments (2)
CHANGE OF NAME Recorded Nov 17, 2016
From: BUDDHIST TZU CHI GENERAL HOSPITAL
To: HUALIEN TZU CHI HOSPITAL, BUDDHIST TZU CHI MEDICAL FOUNDATION
Reel/Frame 040634/0207 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 6, 2011
From: DING, DAH-CHING
To: BUDDHIST TZU CHI GENERAL HOSPITAL
Reel/Frame 026859/0825 →
Continuity (1)
Related Publication 20130059373A1 · Mar 7, 2013