Granted Patent B2

US 9,598,459 · App. 15/222,062 · Granted Mar 21, 2017

Inventors: Randice Lisa Altschul (Cliffside Park, NJ); Neil David Theise (New York, NY); Andreas J. Kesel (Munich, DE); Myron Rapkin (Indianapolis, IN); Rebecca O'Brien (Shell Knob, MO); Anthony R. Arment (Fairborn, OH)

Assignee: Pop Test Oncology LLC

C07J41/0005A61K31/58A61K31/7068A61K45/06C07H19/06C07J17/00

Abstract

Claims (28)

1. A compound selected from the group consisting of:

PT155:

or pharmaceutically acceptable salts thereof;

PT156:

or pharmaceutically acceptable salts thereof;

PT157:

or pharmaceutically acceptable salts thereof;

PT158:

or pharmaceutically acceptable salts thereof;

TCY1:

or pharmaceutically acceptable salts thereof; and,

combinations thereof.

2. A pharmaceutical composition comprising a therapeutically effective amount of at least one active agent, wherein the active agent is selected from the group consisting of:

PT155:

or pharmaceutically acceptable salts thereof;

PT156:

or pharmaceutically acceptable salts thereof;

PT157:

or pharmaceutically acceptable salts thereof;

PT158:

or pharmaceutically acceptable salts thereof;

TCY1:

or pharmaceutically acceptable salts thereof; combinations thereof;

and

at least one pharmaceutically acceptable excipient.

3. The pharmaceutical composition of claim 2 in a dosage form selected from the group consisting of a minicapsule, a capsule, a tablet, an implant, a troche, a lozenge, a minitablet, a temporary or permanent suspension, an injectable, an ovule, a suppository, a wafer, a chewable tablet, a quick or fast dissolving tablet, an effervescent tablet, a buccal or sublingual solid, a granule, a film, a sprinkle, a pellet, a topical formulation, a patch, a bead, a pill, a powder, a triturate, a smart pill, a smart capsule, a platelet, a strip, and a sachet.

4. The pharmaceutical composition of claim 2 in a dosage form for topical application, and at least one pharmaceutically acceptable excipient.

5. The pharmaceutical composition of claim 2 in a dosage form for topical application wherein said formulation is in a form selected from the group consisting of: cream, lotion, gel, oil, ointment, suppository, spray, foam, liniment, aerosol, buccal and sublingual tablet or a transdermal device or patch for absorption through the skin or mucous membranes.

Assignments (1)

Continuity (24)