Antimicrobial glass compositions, glasses and polymeric articles incorporating the same
Embodiments of the present invention pertain to antimicrobial glass compositions, glasses and articles. The articles include a glass, which may include a glass phase and a cuprite phase. In other embodiments, the glasses include as plurality of Cu 1+ ions, a degradable phase including B 2 O 3 , P 2 O 5 and K 2 O and a durable phase including SiO 2 . Other embodiments include glasses having a plurality of Cu 1+ ions disposed on the surface of the glass and in the glass network and/or the glass matrix. The article may also include a polymer. The glasses and articles disclosed herein exhibit a 2 log reduction or greater in a concentration of at least one of Staphylococcus aureus, Enterobacter aerogenes, Pseudomonas aeruginosa bacteria, Methicillin Resistant Staphylococcus aureus , and E. coli , under the EPA Test Method for Efficacy of Copper Alloy as a Sanitizer testing conditions and under Modified JIS Z 2801 for Bacteria testing conditions. In some embodiments, the glass and articles exhibit a 2 log reduction or greater in a concentration of Murine Norovirus under Modified JIS Z 2801 Test for Viruses testing conditions.
1. An article comprising a glass, wherein the glass comprises a cuprite phase comprising a plurality of Cu 1+ ions;
a first phase comprising at least one of B 2 O 3 , P 2 O 5 and R 2 O, wherein R is selected from the group consisting of K, Na, Li, Rb, Cs and combinations thereof; and
a second phase,
wherein the glass comprises a surface portion having a depth of less than about 5 nanometers (nm), the surface portion comprising a plurality of copper ions wherein at least 75% of the plurality of copper ions are Cu 1+ .
2. The article of claim 1 , further comprising a polymer, wherein the polymer comprises a thermoplastic polymer, a polyolefin, an injection moldable thermosetting polymer or combinations thereof.
3. The article of claim 2 , further comprising a glass to polymer ratio in the range from about 10:90 to about 90:10, based on weight percent.
4. The article of claim 1 , further exhibiting any one or more of
a 2 log reduction or greater in a concentration of any one or more of Staphylococcus aureus, Enterobacter aerogenes, Pseudomonas aeruginosa bacteria, Methicillin Resistant Staphylococcus aureus , and E. coli , under the EPA Test Method for Efficacy of Copper Alloy as a Sanitizer testing conditions,
a 4 log reduction or greater in a concentration of any one or more of Staphylococcus aureus, Enterobacter aerogenes, Pseudomonas aeruginosa bacteria, Methicillin Resistant Staphylococcus aureus , and E. coli , under the JIS Z 2801 (2000) testing conditions or a Modified JIS Z 2801 Test for Bacteria, and
a 4 log reduction or greater in a concentration of Murine Norovirus , under a Modified JIS Z 2801 Test for Viruses.
5. The article of claim 1 , wherein the cuprite phase is dispersed in at least one of the first phase and the second phase.
6. The article of claim 1 , wherein the second phase comprises SiO 2 .
7. The article of claim 1 , wherein the first phase comprises Cu′.
8. The article of claim 1 , wherein the cuprite phase comprises at least about 10 weight percent of the glass.
9. The article of claim 1 , wherein the glass comprises a surface, a glass network and a glass matrix, and wherein the plurality of Cu 1+ ions is disposed on the surface and in at least one of the glass network and the glass matrix.