IP Library Granted Patent US 9,655,529
Granted Patent B2
US 9,655,529 · App. 14/174,329 · Granted May 23, 2017

Left atrial pressure measurement method and left atrial pressure measurement device

Inventors: Mikio Aoki (Suwa, JP); Kazunori Uemura (Ibaraki, JP); Masaru Sugimachi (Toyonaka, JP)
Assignees: SEIKO EPSON CORPORATION; NATIONAL CEREBRAL AND CARDIOVASCULAR CENTER
A61B5/021A61B8/48A61B8/488A61B8/5223A61B8/04A61B8/0883
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Quick Facts
Patent No.
US 9,655,529
App. No.
14/174,329
Granted
May 23, 2017
Kind
B2
Abstract

A left atrial pressure measurement device includes: a measurement section that measures a first index value that indicates performance of a right ventricle, and a second index value that indicates performance of a left ventricle; and a calculation section that calculates a left atrial pressure using the first index value, the second index value, and a measured right atrial pressure.

Claims (45)

1. A left atrial pressure measurement method comprising:

causing a transthoracic echocardiographic device to acquire an ultrasonic echo using one or two pad-type ultrasonic probes attached to a chest of a subject to continuously measure a velocity of a tricuspid annulus and a velocity of a mitral annulus;

causing a heartbeat measurement device to continuously measure a heartbeat of the subject;

causing a processing device to calculate a relative ratio S T /S M of the velocity of the tricuspid annulus to the velocity of the mitral annulus when the heartbeat is in a systolic phase, wherein S T is peak systolic tricuspid annular velocity and S M is peak systolic mitral annular velocity; and

causing the processing device to calculate a left atrial pressure based on an expression (J) or (K) using the relative ratio S T /S M and a given right atrial pressure of the subject,

Left atrial pressure=EXP[ C 1·ln(right atrial pressure)+ C 2·ln( S T /S M )+ C 3]  (J)

Left atrial pressure= B 1·right atrial pressure·( S T /S M )+ B 2  (K)

where, C1, C2, C3, B1, and B2 are constants,

the left atrial pressure being calculated by measuring the velocity of the tricuspid annulus, the velocity of the mitral annulus, the heartbeat, and the right atrial pressure as measured values with respect to a heart of the subject.

2. The left atrial pressure measurement method as defined in claim 1 ,

the calculating of the relative ratio including calculating a relative ratio of a maximum value or an average value of the velocity of the tricuspid annulus in the systolic phase to a maximum value or an average value of the velocity of the mitral annulus in the systolic phase.

3. The left atrial pressure measurement method as defined in claim 1 ,

the calculating of the left atrial pressure including continuously calculating the left atrial pressure.

4. The left atrial pressure measurement method as defined in claim 1 , further comprising:

measuring a jugular venous pressure or a peripheral venous pressure; and

determining the right atrial pressure from the measured jugular venous pressure or peripheral venous pressure.

5. A left atrial pressure measurement method comprising:

causing a transthoracic echocardiographic device to acquire an ultrasonic echo using one or two pad-type ultrasonic probes attached to a chest of a subject to continuously measure an acceleration of a tricuspid annulus and an acceleration of a mitral annulus;

causing a heartbeat measurement device to continuously measure a heartbeat of the subject;

causing a processing device to calculate a relative ratio S T /S M of the acceleration of the tricuspid annulus to the acceleration of the mitral annulus when the heartbeat is in a systolic phase, wherein S T is peak systolic tricuspid annular acceleration and S M is peak systolic mitral annular acceleration; and

causing the processing device to calculate a left atrial pressure based on an expression (J) or (K) using the relative ratio S T /S M and a given right atrial pressure of the subject,

Left atrial pressure=EXP[ C 1·ln(right atrial pressure)+ C 2·ln( S T /S M )+ C 3]  (J)

Left atrial pressure= B 1·right atrial pressure·( S T /S M )+ B 2  (K)

where, C1, C2, C3, B1, and B2 are constants,

the left atrial pressure being calculated by measuring the acceleration of the tricuspid annulus, the acceleration of the mitral annulus, the heartbeat, and the right atrial pressure as measured values with respect to a heart of the subject.

6. The left atrial pressure measurement method as defined in claim 5 ,

the calculating of the relative ratio including calculating a relative ratio of a maximum value or an average value of the acceleration of the tricuspid annulus in the systolic phase to a maximum value or an average value of the acceleration of the mitral annulus in the systolic phase.

7. The left atrial pressure measurement method as defined in claim 5 ,

the calculating of the left atrial pressure including continuously calculating the left atrial pressure.

8. A system that measures a left atrial pressure of a subject, the system comprising:

a transthoracic echocardiographic device that acquires an ultrasonic echo using one or two pad-type ultrasonic probes configured to be attached to a chest of the subject to continuously measure a velocity of a tricuspid annulus and a velocity of a mitral annulus;

a heartbeat measurement device that continuously measures a heartbeat of the subject; and

a processing device that calculates a relative ratio S T /S M of the velocity of the tricuspid annulus to the velocity of the mitral annulus when the heartbeat is in a systolic phase, wherein S T is peak systolic tricuspid annular velocity and S M is peak systolic mitral annular velocity, and calculates the left atrial pressure based on an expression (J) or (K) using the relative ratio S T /S M and a given right atrial pressure of the subject,

Left atrial pressure=EXP[ C 1·ln(right atrial pressure)+ C 2·ln( S T /S M )+ C 3]  (J)

Left atrial pressure= B 1·right atrial pressure·( S T /S M )+ B 2  (K)

where, C1, C2, C3, B1, and B2 are constants,

the left atrial pressure being calculated by measuring the velocity of the tricuspid annulus, the velocity of the mitral annulus, the heartbeat, and the right atrial pressure as measured values with respect to a heart of the subject.

9. A system that measures a left atrial pressure of a subject, the system comprising:

a transthoracic echocardiographic device that acquires an ultrasonic echo using one or two pad-type ultrasonic probes configured to be attached to a chest of the subject to continuously measure an acceleration of a tricuspid annulus and an acceleration of a mitral annulus;

a heartbeat measurement device that continuously measures a heartbeat of the subject; and

a processing device that calculates a relative ratio S T /S M of the acceleration of the tricuspid annulus to the acceleration of the mitral annulus when the heartbeat is in a systolic phase, wherein S T is peak systolic tricuspid annular acceleration and S M is peak systolic mitral annular acceleration, and calculates the left atrial pressure based on an expression (J) or (K) using the relative ratio S T /S M and a given right atrial pressure of the subject,

Left atrial pressure=EXP[ C 1·ln(right atrial pressure)+ C 2·ln( S T /S M )+ C 3]  (J)

Left atrial pressure= B 1·right atrial pressure·( S T /S M )+ B 2  (K)

where, C1, C2, C3, B1, and B2 are constants,

the left atrial pressure being calculated by measuring the acceleration of the tricuspid annulus, the acceleration of the mitral annulus, the heartbeat, and the right atrial pressure as measured values with respect to a heart of the subject.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 6, 2014
From: AOKI, MIKIO; UEMURA, KAZUNORI; SUGIMACHI, MASARU
To: SEIKO EPSON CORPORATION; NATIONAL CEREBRAL AND CARDIOVASCULAR CENTER
Reel/Frame 032160/0697 →
Priority Claims (1)
JP 2013-024296 · Feb 12, 2013 · national
Continuity (1)
Related Publication 20140228683A1 · Aug 14, 2014