IP Library › Granted Patent US 9,655,944
Granted Patent B2
US 9,655,944 · App. 15/185,273 · Granted May 23, 2017

Inhibitors of hepatitis C virus

Inventors: Kyla Bjornson (San Lorenzo, CA); Eda Canales (San Mateo, CA); Jeromy J. Cottell (Redwood City, CA); Kapil K. Karki (Foster City, CA); Ashley A. Katana (North Olmsted, OH); Darryl Kato (San Francisco, CA); Tetsuya Kobayashi (Pleasanton, CA); John O. Link (San Francisco, CA); Ruben Martinez (San Diego, CA); Barton W. Phillips (San Mateo, CA); Hyung-jung Pyun (Fremont, CA); Michael Sangi (San Mateo, CA); Adam J. Schrier (Redwood City, CA); Dustin Siegel (Half Moon Bay, CA); James G. Taylor (Burlingame, CA); Chinh V. Tran (San Diego, CA); Teresa A. Trejo Martin (Belmont, CA); Randall W. Vivian (San Mateo, CA); Zheng-Yu Yang (Palo Alto, CA); Jeff Zablocki (Los Altos, CA); Sheila Zipfel (San Mateo, CA)
Assignee: GILEAD SCIENCES, INC.
A61K38/06A61K31/4745A61K31/4985A61K31/506A61K31/519A61K38/21A61K45/06C07D498/16C07D498/22C07K5/08C07K5/0808C07K5/0812C07K5/0827A61K38/00
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Quick Facts
Patent No.
US 9,655,944
App. No.
15/185,273
Granted
May 23, 2017
Kind
B2
Abstract

Compounds of Formula I are disclosed As well as pharmaceutically acceptable salts thereof. Methods of using said compounds and pharmaceutical compositions containing said compounds are also disclosed.

Claims (4)

1. A method of treating hepatitis C virus infection in a patient in need thereof, comprising administering to said patient a therapeutically effective amount of a compound of compound of Formula IVc:

or a stereoisomer, or a mixture of stereoisomers, or a pharmaceutically acceptable salt thereof.

2. The method of claim 1 wherein the compound is a compound of Formula IVd:

or a pharmaceutically acceptable salt thereof.

Assignments (3)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 22, 2019
From: GILEAD SCIENCES, INC.
To: GILEAD PHARMASSET LLC
Reel/Frame 048958/0911 →
CORRECTIVE ASSIGNMENT TO CORRECT THE 19TH INVENTOR LAST NAME PREVIOUSLY RECORDED ON REEL 039208 FRAME 0681. ASSIGNOR(S) HEREBY CONFIRMS THE LAST NAME OF THE 19TH INVENTOR SHOULD BE Recorded Aug 24, 2016
From: BJORNSON, KYLA; CANALES, EDA; COTTELL, JEROMY J.; KARKI, KAPIL K.; KATANA, ASHLEY A.; KATO, DARRYL; KOBAYASHI, TETSUYA; LINK, JOHN O.; ZIPFEL, SHEILA; MARTINEZ, RUBEN; SCHRIER, ADAM J.; SIEGEL, DUSTIN; TAYLOR, JAMES G.; TRAN, CHINH V.; TREJO-MARTIN, TERESA A; VIVIAN, RANDALL W.; YANG, ZHENG-YU; ZABLOCKI, JEFF; PHILLIPS, BARTON W.; PYUN, HYUNG-JUNG; SANGI, MICHAEL
To: GILEAD SCIENCES, INC.
Reel/Frame 039800/0560 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 21, 2016
From: BJORNSON, KYLA; CANALES, EDA; COTTELL, JEROMY J.; KARKI, KAPIL K.; KATANA, ASHLEY A.; KATO, DARRYL; KOBAYASHI, TETSUYA; LINK, JOHN O.; ZIPFEL, SHEILA; MARTINEZ, RUBEN; SCHRIER, ADAM J.; SIEGEL, DUSTIN; TAYLOR, JAMES G.; TRAN, CHINH V.; TREJO-MARTIN, TERESA A.; VIVIAN, RANDALL W.; YANG, ZHENG-YU; ZABLOCKI, JEFF; PHILIPS, BARTON W.; PYUN, HYUNG-JUNG; SANGI, MICHAEL
To: GILEAD SCIENCES, INC.
Reel/Frame 039208/0681 →
Continuity (5)
Continuation 14996961 · Jan 15, 2016
Continuation 13934090 · Jul 2, 2013
Provisional Application 61798524 · Mar 15, 2013
Provisional Application 61667806 · Jul 3, 2012
Related Publication 20160361375A1 · Dec 15, 2016