IP Library › Granted Patent US 9,662,402
Granted Patent B2
US 9,662,402 · App. 14/435,919 · Granted May 30, 2017

Drug delivery conjugates containing unnatural amino acids and methods for using

Inventors: Iontcho Radoslavov Vlahov (West Lafayette, IN); Christopher Paul Leamon (West Lafayette, IN)
Assignee: Endocyte, Inc.
A61K47/48092A61K47/48107C07K7/06
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Quick Facts
Patent No.
US 9,662,402
App. No.
14/435,919
Granted
May 30, 2017
Kind
B2
Abstract

Described herein are drug delivery conjugates for targeted therapy. In particular, described herein are drug delivery conjugates that include polyvalent linkers comprising one or more unnatural amino acids that are useful for treating cancers and inflammatory diseases. The invention described herein pertains to drug delivery conjugates for targeted therapy. In particular, the invention described herein pertains to drug delivery conjugates that include polyvalent linkers comprising one or more unnatural amino acids.

Claims (3)

1. A compound of the formula

or a pharmaceutically acceptable salt thereof.

2. A pharmaceutical composition comprising the compound of claim 1 , or a pharmaceutically acceptable salt thereof, in combination with one or more carriers, diluents, or excipients, or a combination thereof.

Continuity (5)
Provisional Application 61714565 · Oct 16, 2012
Provisional Application 61877317 · Sep 13, 2013
Provisional Application 61865382 · Aug 13, 2013
Provisional Application 61790234 · Mar 15, 2013
Related Publication 20150258203A1 · Sep 17, 2015