Transdermal preparation
A transdermal preparation comprising a multivalent metal chloride, a basic drug having an amino group, and an ester group-containing base material, is useful because of its excellent drug content stability.
1. A transdermal preparation comprising: 0.05% to 5% aluminum chloride by mass based on the total amount of the transdermal preparation, varenicline tartrate, and an acrylic pressure-sensitive adhesive; wherein the transdermal preparation is laminated in a layer form on a backing and thereby formed in a patch shape.
2. A transdermal preparation comprising: 0.05% to 5% aluminum chloride by mass based on the total amount of the transdermal preparation, varenicline tartrate, and an acrylic pressure-sensitive adhesive; wherein the transdermal preparation is formed in a form selected from the group consisting of a paste form, a cream form, a jelly form, a gel form, a milky liquid form and a liquid form.
3. The transdermal preparation according to claim 1 , wherein the aluminum chloride and the varenicline tartrate are dispersed or dissolved in the acrylic pressure-sensitive adhesive.
4. A transdermal preparation comprising: 0.05% to 5% aluminum chloride by mass based on the total amount of the transdermal preparation, varenicline tartrate, and an acrylic pressure-sensitive adhesive; wherein a drug layer containing the aluminum chloride and the varenicline tartrate is formed on a formed product composed of the acrylic pressure-sensitive adhesive.
5. The transdermal preparation according to claim 4 , wherein the formed product is a microneedle.
6. The transdermal preparation according to claim 2 , wherein the aluminum chloride and the varenicline tartrate are dispersed or dissolved in the acrylic pressure-sensitive adhesive.