Composition for the treatment of burns, diabetic wounds, other types of wounds and subsequently greatly reduced scarring
Antimicrobial peptides represent a relatively new discovery in the immune system path-way. Recent designs of synthetically engineered antimicrobial peptides have demonstrated increased potency and efficacy/tolerability, enhanced specificity, and reduced toxicity in comparison. One such peptide, XYLENTRA, has shown/demonstrated significant promise from significant in vitro studies against a large number of pathogens. Additionally, extensive animal studies have shown that the XYLENTRA is an antimicrobial peptide against a large number of pathogens. The XYLENTRA is also solute resistant. The test compound Xylentra® has shown/demonstrated significant antibacterial activity on test organisms Staphylococcus aureus MTCC 96 and Pseudomonas aeroginosa. MTCC 741. A substantial decrease in the microbial population level was observed in animals treated with peptide using the protocol described in detail in the application.
1. A wound cream composition comprising anti-microbial peptide SEQ ID NO: 1.
2. The wound cream composition of claim 1 , further comprising compounds 1-5 and 7-13 according to Table 1.
3. The wound cream composition of claim 2 exhibiting a wound healing efficacy of about 94% wherein said wound healing efficacy is demonstrated by complete wound closure in patient with partial thickness burns.
4. The wound cream composition of claim 2 exhibiting increased efficacy in controlling secondary infection in patients with burn wounds.