IP Library Granted Patent US 9,743,891
Granted Patent B2
US 9,743,891 · App. 14/413,279 · Granted Aug 29, 2017

Super-resolution tomosynthesis imaging systems and methods

Inventors: Andrew D. A. Maidment (Villanova, PA); Raymond J. Acciavatti (Newtown Square, PA); Predrag Bakic (Philadelphia, PA); Susan Ng (Villanova, PA); Peter A. Ringer (Allentown, PA); Johnny Kuo (Lancaster, PA)
Assignees: The Trustees of the University of Pennsylvania; Real Time Tomography, LLC
A61B6/025A61B6/4233A61B6/4452A61B6/502A61B6/54
View Patent ↗
Loading inventors, assignments & file history…
Monitor This Case
Get email alerts when status or documents change.
Order Certified Copies
Most orders are placed with the USPTO same day — all within 24 business hours.
Order via The Patent Place →
Pre-filled with this patent's details
Quick Facts
Patent No.
US 9,743,891
App. No.
14/413,279
Granted
Aug 29, 2017
Kind
B2
Abstract

Tomosynthesis imaging methods, systems, and apparatus include a source to emit penetrating particles toward an object, a detector to acquire a series of projection images responsive to the penetrating particles, and a positioning system to position the source with respect to the object and the detector. An imaging system controls the positioning apparatus, source, and detector to acquire images along a primary scan direction with offsets in a secondary scan direction. An oscillatory velocity may be applied to the source to reduce focal spot blur. Tomographic volumes are constructed that are capable of exhibiting super-resolution from data representing the acquired series of projection images taking the primary scan direction and the offsets into consideration.

Claims (33)

1. A super-resolution digital tomosynthesis system for imaging an object, the super-resolution digital tomosynthesis system comprising:

at least one source configured to emit penetrating particles toward an object;

at least one detector comprising an array of pixels in a detector plane configured to acquire a series of projection images of the object in response to the penetrating particles from the at least one source, pixels within the array of pixels having a fixed pixel dimension;

a positioning apparatus configured to position the at least one source with respect to the at least one detector; and

an imaging system coupled to the at least one source, the at least one detector, and the positioning apparatus, the imaging system configured to:

control the positioning apparatus to position the at least one source with respect to the at least one detector to introduce a primary scan motion of the imaging system with respect to the object, wherein the primary scan motion of the source forms a primary plane, and to introduce at least one offset of the detector along a secondary direction with respect to the object, the secondary direction being in the detector plane perpendicular to the primary plane, and the at least one offset being a non-integer multiple of the pixel dimension;

control the at least one source and the at least one detector to acquire the series of projection images with the primary scan motion and the introduced at least one offset in the secondary direction; and

construct a tomographic volume capable of exhibiting super-resolution from data representing the acquired series of projection images taking the primary scan motion and the at least one offset into consideration.

2. The super-resolution digital tomosynthesis system of claim 1 , wherein the positioning apparatus is coupled to the at least one source and the at least one detector and wherein the positioning apparatus is configured to move the at least one source in the primary scan motion and to move the at least one detector in the secondary direction.

3. The super-resolution digital tomosynthesis system of claim 2 , wherein the positioning apparatus comprises:

a first electromechanical drive coupled to the at least one source to move the at least one source along the primary scan motion;

a second electromechanical drive coupled to the at least one detector to move the at least one detector along the secondary direction.

4. The super-resolution digital tomosynthesis system of claim 1 , wherein the positioning apparatus is coupled to the at least one source and wherein the positioning apparatus is configured to move the at least one source with respect to the at least one detector, by moving the at least one source along the primary scan motion and in the secondary direction.

5. The super-resolution digital tomosynthesis system of claim 1 , wherein the positioning apparatus is coupled to the at least one detector and wherein the positioning apparatus is configured to move the at least one detector with respect to the at least one source, by moving the at least one detector along the primary scan motion and in the secondary direction.

6. The super-resolution digital tomosynthesis system of claim 1 , wherein the positioning apparatus comprises:

a conveyer belt configured to receive the object and to move the object in the primary scan motion past the at least one source and the at least one detector.

7. A super-resolution digital tomosynthesis method for imaging an object, the method comprising:

positioning at least one source of penetrating particles and at least one detector with respect to the object with a primary scan motion, wherein the primary scan motion of the at least one source forms a primary plane, the at least one detector comprising an array of pixels in a detector plane, pixels within the array of pixels having a fixed pixel dimension;

introducing at least one offset of the detector in a secondary direction with respect to the at least one source of penetrating particles, the secondary direction being in the detector plane perpendicular to the primary plane, and the at least one offset being a non-integer multiple of the pixel dimension;

acquiring a series of images with the primary scan motion and the introduced at least one offset; and

constructing a tomographic volume capable of exhibiting super-resolution from data representing the acquired series of projection images taking the primary scan motion and the at least one offset into consideration.

8. The super-resolution digital tomosynthesis method of claim 7 , further comprising:

displaying super-resolution images from the tomographic volume.

9. The super-resolution digital tomosynthesis method of claim 7 , wherein the at least one offset is introduced as the at least one source of penetrating particles is positioned with respect to at least one detector and the object with the primary scan motion.

10. The super-resolution digital tomosynthesis method of claim 7 , wherein the positioning step comprises a smooth oscillatory velocity that is reduced during the acquiring of each image of the series of images.

11. The super-resolution digital tomosynthesis method of claim 7 , wherein the positioning step comprises:

moving the at least one source of penetrating particles along the primary scan motion.

12. The super-resolution digital tomosynthesis method of claim 11 , wherein the introducing step comprises:

moving the at least one detector along the secondary direction.

13. The super-resolution digital tomosynthesis method of claim 12 , wherein the introducing step comprises:

moving the at least one source along the secondary direction.

14. The super-resolution digital tomosynthesis method of claim 11 , wherein the positioning step comprises:

moving the object along the primary scan motion.

Assignments (3)
CONFIRMATORY LICENSE Recorded Aug 17, 2016
From: UNIVERSITY OF PENNSYLVANIA
To: US ARMY, SECRETARY OF THE ARMY
Reel/Frame 039707/0717 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 20, 2016
From: MAIDMENT, ANDREW D. A.; ACCIAVATTI, RAYMOND J.; BAKIC, PREDRAG; NG, SUSAN; RINGER, PETER A.; KUO, JOHNNY
To: THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA; REAL TIME TOMOGRAPHY, LLC
Reel/Frame 037536/0763 →
CONFIRMATORY LICENSE Recorded Mar 6, 2015
From: UNIVERSITY OF PENNSYLVANIA
To: NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT
Reel/Frame 035137/0460 →
Continuity (3)
Provisional Application 61669459 · Jul 9, 2012
Provisional Application 61763310 · Feb 11, 2013
Related Publication 20150201890A1 · Jul 23, 2015