IP Library Granted Patent US 9,795,584
Granted Patent B2
US 9,795,584 · App. 14/907,840 · Granted Oct 24, 2017

Treating an atypical protein kinase C enzyme abnormality

Inventors: Robert Vito Farese (St. Petersburg, FL); Mini Paliyath Sajan (Wesley Chapel, FL)
Assignee: University of South Florida
A61K31/341A61K31/122
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Quick Facts
Patent No.
US 9,795,584
App. No.
14/907,840
Granted
Oct 24, 2017
Kind
B2
Abstract

Provided herein are compounds, compositions, pharmaceutical formulations, methods of treating and methods of using aPKC inhibitors for treating and/or preventing of aPKC abnormalities.

Claims (5)

1. A method of treating insulin resistance in a subject in need thereof comprising:

administering an effective amount of 2-acetylcyclopentane-1,3-dione (ACPD) to the subject in need thereof, wherein the subject in need thereof has insulin resistance.

2. The method of claim 1 , wherein the effective amount ranges from about 0.001 mg to about 1,000 mg.

3. The method of claim 1 , wherein the effective amount is administered in a dosage form formulated for oral, vaginal, intravenous, transdermal, subcutaneous, intraperitoneal, or intramuscular administration.

4. The method of claim 1 , wherein the effective amount ranges from about 0.001 mg to about 100 mg.

Assignments (3)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 26, 2018
From: UNIVERSITY OF SOUTH FLORIDA
To: UNIVERSITY OF SOUTH FLORIDA; THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS OFFICE OF GENERAL COUNSEL - PSG IV (024)
Reel/Frame 044742/0107 →
CONFIRMATORY LICENSE Recorded Jun 30, 2016
From: UNIVERSITY OF SOUTH FLORIDA
To: NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT
Reel/Frame 039217/0804 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 27, 2016
From: FARESE, ROBERT VITO; SAJAN, MINI PALIYATH
To: UNIVERSITY OF SOUTH FLORIDA
Reel/Frame 037592/0360 →
Continuity (2)
Provisional Application 61859875 · Jul 30, 2013
Related Publication 20160175274A1 · Jun 23, 2016