IP Library › Granted Patent US 9,795,669
Granted Patent B2
US 9,795,669 · App. 14/969,483 · Granted Oct 24, 2017

Lipidated immune response modifier compound compositions, formulations, and methods

Inventor: Paul D. Wightman (St. Paul, MN)
Assignee: 3M INNOVATIVE PROPERTIES COMPANY
A61K39/39A61K9/0019A61K9/10A61K9/127A61K31/437A61K31/47A61K39/0011A61K47/26C07D471/04A61K2039/55511A61K2039/55555A61K2039/55572A61K2039/572
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Quick Facts
Patent No.
US 9,795,669
App. No.
14/969,483
Granted
Oct 24, 2017
Kind
B2
Abstract

The compound N-(4-{[4-amino-2-butyl-1H-imidazo[4,5-c]quinolin-1-yl]oxyl}butyl)octadecanamide is a useful drug compound for enhancing immune response and can be used, for example, as a vaccine adjuvant and a cancer treatment.

Claims (2)

1. A method of inducing formation of tumor necrosis factor in a human or animal in need thereof, the method comprising administering the compound N-(4-{[4-amino-2-butyl-1H-imidazo[4,5-c]quinolin-1-yl]oxy}butyl)-octadecanamide, or a pharmaceutically acceptable salt thereof.

2. The method of claim 1 , wherein the compound is in a liposome formulation.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 1, 2024
From: 3M INNOVATIVE PROPERTIES COMPANY
To: SOLVENTUM INTELLECTUAL PROPERTIES COMPANY
Reel/Frame 066430/0295 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 19, 2016
From: WIGHTMAN, PAUL D.
To: 3M INNOVATIVE PROPERTIES COMPANY
Reel/Frame 039481/0031 →
Continuity (3)
Division 13817214
Provisional Application 61374512 · Aug 17, 2010
Related Publication 20160175433A1 · Jun 23, 2016