IP Library › Granted Patent US 9,809,577
Granted Patent B2
US 9,809,577 · App. 15/103,749 · Granted Nov 7, 2017

Biaryl inhibitors of Bruton's tyrosine kinase

Inventors: Brian T. Hopkins (Newton, MA); Bin Ma (Arlington, MA); Timothy Raymond Chan (Newton, MA); Lihong Sun (Lexington, MA); Lei Zhang (Westford, MA); Gnanasambandam Kumaravel (Westford, MA); Joseph P. Lyssikatos (Cambridge, MA); Kevin Koch (Cambridge, MA); Hua Miao (Newton, MA)
Assignee: Biogen MA Inc.
C07D403/12C07D401/14C07D409/14C07D413/14C07D417/12C07D417/14C07D487/04C07D495/04C07D513/04
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Quick Facts
Patent No.
US 9,809,577
App. No.
15/103,749
Granted
Nov 7, 2017
Kind
B2
Abstract

The present invention provides compounds and compositions thereof which are useful as inhibitors of Bruton's tyrosine kinase and which exhibit desirable characteristics for the same.

Claims (3)

1. A compound of formula I-21:

or a pharmaceutically acceptable salt thereof.

2. A pharmaceutical composition comprising a compound of claim 1 and a pharmaceutically acceptable excipient.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 27, 2016
From: HOPKINS, BRIAN T.; MA, BIN; CHAN, TIMOTHY RAYMOND; SUN, LIHONG; ZHANG, LEI; KUMARAVEL, GNANASAMBANDAM; LYSSIKATOS, JOSEPH P.; KOCH, KEVIN; MIAO, HUA
To: BIOGEN MA INC.
Reel/Frame 040503/0521 →
Continuity (2)
Provisional Application 61914886 · Dec 11, 2013
Related Publication 20160311802A1 · Oct 27, 2016