Rolled collagen carrier
The invention relates to a process for the preparation of a rolled compressed collagen carrier and a process for un-rolling said rolled compressed collagen carrier. Said rolled compressed collagen carrier is ready for use in minimally invasive surgery. The invention also relates to a rolled compressed collagen carrier for use in the prevention or treatment of injury associated with performing minimally invasive surgery.
1. A form-stable coiled hemostatic collagen carrier
comprising a collagen sponge with a coating layer on the top surface of the collagen sponge, the coating layer comprising thrombin and fibrinogen, and
having the shape of an elongate element with a number of windings of the collagen carrier about the longitudinal axis of the elongate element and at least one outer winding(s),
wherein
the at least one outer winding(s) are orientated so that the coating layer constitutes the outer surface of each outer winding,
and wherein
the coiled collagen carrier is form-stable and defines a collagen carrier in a coiled configuration where said at least one outer winding(s) proceed along a spiral in a cross section of the collagen carrier.
2. A coiled collagen carrier according to claim 1 , wherein the collagen carrier in an unrolled configuration is a rectangular sheet.
3. A coiled collagen carrier according to claim 1 , comprising three, four or five windings.
4. A coiled collagen carrier according to claim 1 , wherein the coiled collagen carrier has a cylindrical shape with an outer diameter of less than 12 mm.
5. A coiled collagen carrier according to claim 1 , wherein the coating layer has no through-going cracks.
6. A packed coiled collagen carrier, comprising a coiled collagen carrier according to claim 1 arranged in a container.
7. A method for delivering a coiled collagen carrier according to claim 1 to a target location, comprising the step of passing said coiled collagen carrier through an orifice or access tube to the target location.
8. A method of surgery comprising administering to a patient in need thereof the coiled collagen carrier according to claim 1 .
9. A method of preventing or treating an injury associated with performing minimally invasive surgery in a patient, comprising administering to a patient in need thereof the coiled collagen carrier according to claim 1 .
10. A method of preventing or treating an injury associated with performing endoscopic surgery in a patient, comprising administering to a patient in need thereof the coiled collagen carrier according to claim 1 .
11. A method of preventing injury to or treating a tissue in need of sealing and/or glueing, comprising administering to a patient in need thereof the coiled collagen carrier according to claim 1 .