IP Library Granted Patent US 9,820,651
Granted Patent B2
US 9,820,651 · App. 13/987,683 · Granted Nov 21, 2017

Methods and devices for labeling and/or matching

Inventors: Juerg Tschirren (Iowa City, IA); Milan Sonka (Iowa City, IA); Joseph Reinhardt (Iowa City, IA); Geoffrey McLennan (Iowa City, IA); Eric Hoffman (Iowa City, IA)
Assignee: University of Iowa Research Foundation
A61B5/00A61B5/0033A61B5/08G06F19/3437G06K2209/05G06K2209/053G06K2209/055
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Quick Facts
Patent No.
US 9,820,651
App. No.
13/987,683
Granted
Nov 21, 2017
Kind
B2
Abstract

Devices, such as computer readable media, and methods, such as automated methods, for labeling and/or matching. Some of the devices and methods are particularly useful for anatomical labeling of human airway trees. Some of the devices and methods are particularly useful for matching branch-points of human airway trees from represented in two or more graphs.

Claims (26)

1. A non-transitory computer readable medium comprising machine readable instructions for:

accessing a representation of a target tree, the representation having edges and vertices;

identifying a vertex in the representation that includes a first out-edge, a second out-edge and an in-edge, where the second out-edge is a terminal edge and where a first vertex defines one end of the first out-edge and a second vertex defines one end of the in-edge, and where the vertex, the first vertex, and the second vertex are different from each other; and

introducing an edge to the representation that extends between the first vertex and second vertex,

where the target tree comprises a human airway tree.

2. The computer readable medium of claim 1 , where the representation is based on volumetric image data taken using computed tomography.

3. The computer readable medium of claim 1 , where the representation is based on volumetric image data taken using magnetic resonance.

4. The computer readable medium of claim 1 , where the human airway tree is diseased.

5. The computer readable medium of claim 1 , also including machine readable instructions for:

computing an inheritance relationship for each possible pair of edges in the representation.

6. The computer readable medium of claim 5 , also including machine readable instructions for:

computing a topological distance between each possible pair of edges in the representation.

7. The computer readable medium of claim 1 , also including machine readable instructions for:

deleting from the representation any terminal branch having a length shorter than a pre-defined threshold length.

8. The computer readable medium of claim 1 , also including machine readable instructions for:

accessing data that includes (a) a reference tree having labels and reference tree edges, and (b) inheritance relationship data about some of the reference tree edges; and

building a tree association graph, where the building includes:

adding a first edge to the tree association graph if (i) a corresponding edge of the representation has an inheritance relationship that is the same as the inheritance relationship of a corresponding reference tree edge, and (ii) the topological distance between a vertex of the first edge and a vertex of the corresponding edge of the representation tree is within a certain limit.

9. The computer readable medium of claim 8 , where the tree association graph has a maximum weighted clique, and the computer readable medium also includes machine readable instructions for:

identifying the maximum weighted clique.

10. The computer readable medium of claim 1 , also including machine readable instructions for:

building a tree association graph having segments and sub-trees; and

labeling some segments of the tree association graph in a series of steps, where one sub-tree is labeled in each step.

11. The computer readable medium of claim 1 , also including machine readable instructions for:

building a tree association graph having branch-points and sub-trees; and

labeling some branch-points of the tree association graph in a series of steps, where one sub-tree is labeled in each step.

Assignments (3)
CORRECTIVE ASSIGNMENT TO CORRECT THE ASSIGNEE ADDRESS PREVIOUSLY RECORDED AT REEL: 037276 FRAME: 0429. ASSIGNOR(S) HEREBY CONFIRMS THE ASSIGNMENT. Recorded Dec 29, 2015
From: TSCHIRREN, JUERG; SONKA, MILAN; REINHARDT, JOSEPH; MCLENNAN, GEOFFREY; HOFFMAN, ERIC
To: UNIVERSITY OF IOWA RESEARCH FOUNDATION
Reel/Frame 037397/0075 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 11, 2015
From: TSCHIRREN, JUERG; SONKA, MILAN; REINHARDT, JOSEPH; MCLENNAN, GEOFFREY; HOFFMAN, ERIC
To: UNIVERSITY OF IOWA RESEARCH FOUNDATION
Reel/Frame 037276/0429 →
CONFIRMATORY LICENSE Recorded Oct 30, 2013
From: UNIVERSITY OF IOWA
To: NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT
Reel/Frame 031515/0231 →
Continuity (5)
Continuation 13506302 · Apr 10, 2012
Continuation 11122974 · May 5, 2005
Provisional Application 60568184 · May 5, 2004
Related Publication 20130343628A1 · Dec 26, 2013
Related Publication 20170119251A9 · May 4, 2017