IP Library › Granted Patent US 9,827,006
Granted Patent B2
US 9,827,006 · App. 12/936,173 · Granted Nov 28, 2017

Method and apparatus for tissue grafting

Inventors: Richard R. Anderson (Boston, MA); Michael R. Hamblin (Revere, MA); Dieter Manstein (Coral Gables, FL); William A. Farinelli (Danvers, MA)
Assignee: THE GENERAL HOSPITAL CORPORATION
A61B17/32053A61B17/322A61B10/0233A61B17/32093A61B2017/00752A61B2017/00969A61B2017/306A61B2017/3225
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Quick Facts
Patent No.
US 9,827,006
App. No.
12/936,173
Filed
Oct 12, 2011
Granted
Nov 28, 2017
Kind
B2
Art Unit
3769
USPC
606/13
Abstract

Exemplary embodiments of apparatus and method for harvesting small portions of tissue (“micrografts”) to form grafts can be provided. For example, a hollow tube can be inserted into tissue at a donor site, where a distal end of the hollow tube can have two or more points or extensions to facilitate separation of the micrografts from the surrounding tissue. The exemplary apparatus can be provided that includes a plurality of such tubes for simultaneous harvesting of a plurality of micrografts. The harvested micrografts can have a small dimension, e.g., less than about 1 mm, or less than about 0.3 mm, which can promote healing of the donor site and/or viability of the harvested tissue. The micrografts can be approximately cylindrical or strip-shaped, and can be placed in a biocompatible matrix to form a graft or directly into tissue at the recipient site. Such exemplary micrografts can be obtained from skin or other types of tissue, e.g., various internal organs.

Claims (11)

1. A method for skin grafting comprising:

obtaining a plurality of skin micrografts from a donor site by;

in a first motion simultaneously inserting at least one section of each of a plurality of hollow tubes into the donor site to a depth at or proximal to the dermal/fatty tissue junction to sever and capture the skin micrografts within the tubes,

wherein each hollow tube comprises at least two points provided at a distal end thereof that are configured to facilitate insertion of the at least one section of each of the hollow tubes into the donor site,

wherein an angle is formed by at least one of the points,

wherein an inner diameter of each of the plurality of hollow tubes is between 0.2 mm and 1 mm in order to hold at least one correspondingly sized skin micrograft to facilitate viability of the micrograft and promote healing of the donor site;

in a second motion withdrawing the plurality of hollow tubes from the donor site without rotating the tubes, thereby removing the skin micrografts from the donor site;

removing the plurality of skin micrografts from the plurality of hollow tubes and distributing the skin micrografts at a recipient site to promote tissue growth at the recipient site.

2. The method of claim 1 , wherein an inner diameter of the hollow tubes is between 0.2 mm and 0.5 mm.

3. The method of claim 1 , wherein an inner diameter of the hollow tubes between 0.2 mm and 0.3 mm.

4. The method of claim 1 , wherein the angle formed by at least one of the points is 30 degrees.

Assignments (5)
PATENT SECURITY AGREEMENT Recorded May 28, 2026
From: MEDLINE INDUSTRIES, LP
To: WILMINGTON TRUST, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT
Reel/Frame 075643/0462 →
PATENT SECURITY AGREEMENT Recorded Jun 20, 2025
From: MEDLINE INDUSTRIES, LP
To: WILMINGTON TRUST, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT
Reel/Frame 071672/0100 →
SECURITY INTEREST Recorded Oct 21, 2021
From: MEDLINE INDUSTRIES, LP
To: WILMINGTON TRUST, NATIONAL ASSOCIATION
Reel/Frame 057927/0091 →
SECURITY INTEREST Recorded Oct 21, 2021
From: MEDLINE INDUSTRIES, LP
To: BANK OF AMERICA, N.A.
Reel/Frame 058040/0001 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 27, 2011
From: ANDERSON, RICHARD R.; HAMBLIN, MICHAEL R.; MANSTEIN, DIETER; FARINELLI, WILLIAM A.; FRANCO, WALFRE
To: THE GENERAL HOSPITAL CORPORATION
Reel/Frame 026506/0019 →
Continuity (2)
Provisional Application 61041587 · Apr 1, 2008
Related Publication 20120041430A1 · Feb 16, 2012