IP Library Granted Patent US 9,877,960
Granted Patent B2
US 9,877,960 · App. 14/646,182 · Granted Jan 30, 2018

Learning and memory improver

Inventors: Nobuo Tsuruoka (Osaka, JP); Hiroshi Watanabe (Osaka, JP)
Assignees: SUNTORY HOLDINGS LIMITED; CEREBOS PACIFIC LIMITED
A61K31/495
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Quick Facts
Patent No.
US 9,877,960
App. No.
14/646,182
Granted
Jan 30, 2018
Kind
B2
Abstract

The present invention aims to provide antidementia agents which are free from the problem of side effects and are excellent in safety. The present invention also aims to provide agents for improving learning and memory which are useful for improvement of learning and memory and can be ingested continuously. The present invention provides antidementia agents and agents for improving learning and memory, each comprising a cyclic dipeptide with the 2,5-diketopiperazine structure as an active ingredient.

Claims (6)

1. A method for improving or retarding the progress of a symptom of Alzheimer type dementia, comprising administering to a subject in need thereof an agent comprising 2,5-piperazinedione-3,6-bis(phenylmethyl)-,(3S,6S).

2. The method according to claim 1 , wherein the symptom is depression.

3. The method according to claim 1 , wherein the symptom is reduced learning motivation.

4. The method according to claim 1 , wherein the agent is administered orally.

5. A method for improving learning and memory in a subject having Alzheimer type dementia, comprising administering to a subject in need thereof an agent comprising 2,5-piperazinedione-3,6-bis(phenylmethyl)-,(3S,6S).

6. The method according to claim 5 , wherein the agent is administered orally.

Assignments (2)
MERGER Recorded Aug 23, 2019
From: CEREBOS PACIFIC LIMITED
To: SUNTORY BEVERAGE & FOOD ASIA PTE. LTD.
Reel/Frame 051616/0589 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 5, 2015
From: TSURUOKA, NOBUO; WATANABE, HIROSHI
To: SUNTORY HOLDINGS LIMITED; CEREBOS PACIFIC LIMITED
Reel/Frame 036729/0488 →
Priority Claims (1)
JP 2012-255047 · Nov 21, 2012 · national
Continuity (1)
Related Publication 20150297584A1 · Oct 22, 2015