IP Library › Granted Patent US 9,878,989
Granted Patent B2
US 9,878,989 · App. 15/190,642 · Granted Jan 30, 2018

Heterocyclic compound

Inventors: Takahiro Sugimoto (Kanagawa, JP); Shinkichi Suzuki (Kanagawa, JP); Hiroki Sakamoto (Kanagawa, JP); Masami Yamada (Kanagawa, JP); Minoru Nakamura (Kanagawa, JP); Makoto Kamata (Kanagawa, JP); Kenichiro Shimokawa (Kanagawa, JP); Masataka Murakami (Kanagawa, JP); Jinichi Yonemori (Kanagawa, JP); Takuto Kojima (Kanagawa, JP)
Assignee: Takeda Pharmaceutical Company Limited
C07D265/22C07D413/04C07D413/06C07D413/10C07D413/14C07D417/06C07D471/04C07D491/107C07F7/02C07B2200/07
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Quick Facts
Patent No.
US 9,878,989
App. No.
15/190,642
Granted
Jan 30, 2018
Kind
B2
Abstract

The present invention provides a compound having a cholinergic muscarinic M1 receptor positive allosteric modulator activity, which may be useful as a prophylactic or therapeutic drug for Alzheimer's disease, schizophrenia, pain, sleep disorder, Parkinson's disease dementia, dementia with Lewy bodies and the like. The present invention relates to a compound represented by the formula (I) or a salt thereof: wherein each symbol is as defined in the attached DESCRIPTION.

Claims (3)

1. 8-Chloro-6-((6-chloropyridin-3-yl)methyl)-3-((1S,2S)-2-hydroxycyclopentyl)-7-methyl-2,3-dihydro-4H-1,3-benzoxazin-4-one, or a salt thereof.

2. A pharmaceutical composition comprising:

8-chloro-6-((6-chloropyridin-3-yl)methyl)-3-((1S,2S)-2-hydroxycyclopentyl)-7-methyl-2,3-dihydro-4H-1,3-benzoxazin-4-one or a salt thereof; and a pharmaceutically acceptable carrier.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 31, 2016
From: SUGIMOTO, TAKAHIRO; SUZUKI, SHINKICHI; SAKAMOTO, HIROKI; YAMADA, MASAMI; NAKAMURA, MINORU; KAMATA, MAKOTO; SHIMOKAWA, KENICHIRO; OGINO, MASAKI; KIMURA, EIJI; MURAKAMI, MASATAKA; YONEMORI, JINICHI; KOJIMA, TAKUTO
To: TAKEDA PHARMACEUTICAL COMPANY LIMITED
Reel/Frame 039604/0264 →
Priority Claims (2)
JP 2015-129043 · Jun 26, 2015 · national
JP 2015-206797 · Oct 20, 2015 · national
Continuity (1)
Related Publication 20160376244A1 · Dec 29, 2016