Anti-RhoB antibodies
Anti-RhoB antibodies, compositions comprising the same, and methods for the treatment of autoimmune and inflammatory diseases using the anti-RhoB antibodies are disclosed.
1. An isolated anti-RhoB antibody or fragment thereof which binds SEQ ID NO: 1 or 2.
2. An anti-RhoB antibody which comprises SEQ ID NOs: 10 and 12.
3. An anti-RhoB antibody which comprises SEQ ID NOs: 14 and 16.
4. A composition comprising at least one anti-RhoB antibody or fragment thereof of claim 1 and at least one pharmaceutically acceptable carrier.
5. The composition of claim 4 , wherein said composition further comprises at least one anti-inflammatory agent.
6. The composition of claim 4 , wherein said composition further comprises at least one immunosuppressant.
7. An isolated anti-RhoB antibody or fragment thereof, wherein said antibody or fragment thereof comprises all six complementarity-determining regions (CDRs) of an anti-RhoB antibody comprising SEQ ID NOs: 10 and 12 or an anti-RhoB antibody comprising SEQ ID NOs: 14 and 16.