Cell penetrating peptide, conjugate comprising same, and composition comprising conjugate
The present invention relates to a conjugate of cell penetrating peptide and an active ingredient; and its use. Specifically, a conjugate including a cell penetrating peptide which is a peptide comprising any one amino acid sequence of SEQ ID NO: 1 to SEQ ID NO: 156, a fragment of any one sequence of SEQ ID NO: 1 to SEQ ID NO: 156, or a peptide having above 80% homology with the above-mentioned sequence; and a composition comprising the same are disclosed.
1. A conjugate consisting of a mitochondrial targeting peptide and ferrocene carboxylate, wherein said mitochondrial targeting peptide consists of 30 amino acids or less.
2. The conjugate of claim 1 , wherein the mitochondrial targeting peptide is derived from human telomerase reverse transcriptase (hTERT) enzyme.
3. The conjugate of claim 2 , wherein the mitochondrial targeting peptide comprises SEQ ID NO: 48.
4. The conjugate of claim 1 , wherein the mitochondrial targeting peptide and ferrocene carboxylate are combined via a covalent bond.
5. The conjugate of claim 1 , wherein the mitochondrial targeting peptide and ferrocene carboxylate are combined via a non-covalent bond.
6. A contrasting agent comprising the conjugate of claim 1 .
7. A composition comprising the conjugate of claim 1 and a pharmaceutically acceptable carrier.