Biomarkers for prediction, diagnosis, and monitoring of parkinson's disease
A method for the risk detection, early diagnosis, prognosis, and monitoring of Parkinson's disease in an individual by measuring the amount of specific biomarkers present in a bodily fluid and comparing them to a reference level of biomarkers in a sample from a healthy person, a person previously diagnosed with Parkinson's disease, or an earlier sample from the individual of interest.
1. A kit for determining whether a patient has Parkinson's disease comprising a solid support on which a plurality of agents have been affixed which in combination bind to IGF-I, IGF II, alpha amylase, and at least one or more additional biomarkers selected from the group of biomarkers consisting of Aβ40 and Aβ42 wherein each agent binds to a different single biomarker.
2. The kit of claim 1 , further comprising:
instructions to take the saliva sample from the patient in a similar manner.
3. The kit of claim 1 , further comprising:
instructions to take the saliva sample from the patient within a same time of day window.
4. The kit of claim 1 , further comprising:
instructions to take the saliva sample from the patient in a similar manner and within a same time of day window.