IP Library Granted Patent US 9,940,723
Granted Patent B2
US 9,940,723 · App. 14/968,729 · Granted Apr 10, 2018

Systems and methods to detect and display endovascular features

Inventors: Ajay Gopinath (Bedford, MA); Desmond Adler (Bedford, MA)
Assignee: LIGHTLAB IMAGING, INC.
G06T7/0085A61B5/0066A61B5/02007G06T5/50G06T7/12G06T11/60G06T19/20A61B1/00172A61B5/0084A61B6/504A61B6/5217G06T2200/08G06T2207/10101G06T2207/20104G06T2207/20224G06T2207/30101G06T2210/41G06T2211/404G06T2219/2012
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Quick Facts
Patent No.
US 9,940,723
App. No.
14/968,729
Granted
Apr 10, 2018
Kind
B2
Abstract

In part, the disclosure relates to method for identifying regions of interest in a blood vessel. The method includes the steps of: providing OCT image data of the blood vessel; applying a plurality of different edge detection filters to the OCT image data to generate a filter response for each edge detection filter; identifying in each edge detection filter response any response maxima; combining the response maxima for each edge detection filter response while maintaining the spatial relationship of the response maxima, to thereby create edge filtered OCT data; and analyzing the edge filtered OCT data to identify a region of interest, the region of interest defined as a local cluster of response maxima. In one embodiment, one or more indicia are positioned in one or more panels to emphasize a reference vessel profile as part of a user interface.

Claims (33)

1. A method for identifying regions of interest in a blood vessel, the method comprising the steps of:

providing intravascular image data of the blood vessel;

applying a plurality of different edge detection filters to the intravascular image data to generate a filter response for each edge detection filter;

identifying in each edge detection filter response any response maxima, a local response maxima representing detected edges;

combining the response maxima for each edge detection filter response while maintaining the spatial relationship of the response maxima, to thereby create edge filtered intravascular data;

analyzing the edge filtered intravascular data to identify a region of interest, the region of interest defined as a local cluster of response maxima; and

identifying the region of interest as a calcified region if the region of interest includes at least one vertical edge response maxima,

wherein the plurality of different edge detection filters includes a horizontal edge detection filter and a vertical edge detection filter

wherein the vertical edge detection filter comprises a left edge detection filter and a right edge detection filter.

2. The method of claim 1 , wherein the edge detection filters are based on Gaussian derivatives.

3. The method of claim 1 , wherein the intravascular image data is formatted in polar space or comprises a polar image.

4. The method of claim 1 , wherein the intravascular image data is formatted in Cartesian space or comprises a cross-sectional image.

5. The method of claim 1 , wherein the horizontal edge detection filter comprises a top edge filter and a bottom edge filter.

6. The method of claim 1 , wherein the local maxima are determined by comparing filter responses to a predetermined threshold.

7. The method of claim 1 , wherein the plurality of filters comprises at least a top edge filter, a left edge filter, and a right edge filter.

8. A method for identifying regions of interest in a blood vessel, the method comprising the steps of:

providing intravascular image data of the blood vessel;

applying a plurality of different edge detection filters to the intravascular image data to generate a filter response for each edge detection filter;

identifying in each edge detection filter response any response maxima, a local response maxima representing detected edges;

combining the response maxima for each edge detection filter response while maintaining the spatial relationship of the response maxima, to thereby create edge filtered intravascular data;

analyzing the edge filtered intravascular data to identify a region of interest, the region of interest defined as a local cluster of response maxima; and

identifying the region of interest as a non-calcified region if the region of interest includes no vertical edge response maxima,

wherein the plurality of different edge detection filters includes a horizontal edge detection filter and a vertical edge detection filter,

wherein the vertical edge detection filter comprises a left edge detection filter and a right edge detection filter.

9. A method for identifying regions of interest in a blood vessel, the method comprising the steps of:

providing intravascular mage data of the blood vessel;

applying a plurality of different edge detection filters to the intravascular image data to generate a filter response for each edge detection filter;

identifying in each edge detection filter response any response maxima, a local response maxima representing detected edges;

combining the response maxima for each edge detection filter response while maintaining the spatial relationship of the response maxima, to thereby create edge filtered intravascular data;

analyzing the edge filtered intravascular data to identify a region of interest, the region of interest defined as a local cluster of response maxima;

repeating preceding steps for a plurality of intravascular image frames; and

rendering a two- or three-dimensional model of the blood vessel using the plurality of intravascular image frames, based on the intravascular edge filtered data and the regions of interest,

wherein the model is a three-dimensional longitudinal rendering of the blood vessel, the model including a graphic for indicating a length of the region of interest, the graphic comprising a ring coaxial with the blood vessel with the blood vessel extending through the ring, the ring having a first indicia proportional to the length of healthy tissue and a second indicia proportional to the length of the region of interest.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 28, 2018
From: GOPINATH, AJAY; ADLER, DESMOND
To: LIGHTLAB IMAGING, INC.
Reel/Frame 045468/0104 →
Continuity (3)
Provisional Application 62153816 · Apr 28, 2015
Provisional Application 62091236 · Dec 12, 2014
Related Publication 20160171711A1 · Jun 16, 2016