IP Library Granted Patent US 9,950,323
Granted Patent B2
US 9,950,323 · App. 14/452,172 · Granted Apr 24, 2018

Array plates and methods for making and using same

Inventors: Namyong Kim (Palo Alto, CA); Eng Seng Lim (Singapore, SG); Siah Chong Cheong (Singapore, SG)
Assignee: CURIOX BIOSYSTEMS PTE LTD.
B01L3/5085B01L3/5088B29C43/021B29C43/18B01L2200/12B01L2300/0822B01L2300/0829B01L2300/161
View Patent ↗
Loading inventors, assignments & file history…
Monitor This Case
Get email alerts when status or documents change.
Order Certified Copies
Most orders are placed with the USPTO same day — all within 24 business hours.
Order via The Patent Place →
Pre-filled with this patent's details
Quick Facts
Patent No.
US 9,950,323
App. No.
14/452,172
Granted
Apr 24, 2018
Kind
B2
Abstract

A device includes a first structure with a sheet layer with a plurality of discrete through-holes and a second structure coupled to the first structure. At least a portion of a first surface of the sheet layer of the first structure is exposed from the second structure. A top portion of the sheet layer, including the exposed portion of the first surface of the sheet layer, includes fluorocarbon. The second structure includes a material of a higher surface tension than the top of the sheet layer. A second surface of the sheet layer, opposite to the first surface of the sheet layer, is embedded in the second structure. The second structure extends at least partially into the plurality of discrete through-holes of the first structure.

Claims (36)

1. A method, comprising:

providing a first structure in a mold, the first structure including a sheet layer with a plurality of discrete through-holes, and the sheet layer having a first surface and a second surface that is opposite to the first surface;

providing a heated plastic material into the mold, wherein the heated plastic material has a lower glass transition temperature than the sheet layer;

cooling the plastic material to form a second structure so that the first structure and the second structure are coupled; and

releasing the first structure and the second structure that is coupled with the first structure,

wherein:

the second surface of the sheet layer is embedded in the second structure;

a top portion of the sheet layer, including a portion of the first surface of the sheet layer, includes fluorocarbon;

the second structure includes a material of a higher surface energy than the top portion of the sheet layer; and

the second structure extends at least partially into the plurality of discrete through-holes of the first structure.

2. The method of claim 1 , wherein:

at least 90% of the top portion of the first surface is covered by fluorocarbon.

3. The method of claim 1 , wherein the sheet layer includes at least 96 discrete through-holes.

4. The method of claim 1 , wherein the top portion of the sheet layer includes at least 95% of fluorocarbon by weight.

5. The method of claim 1 , wherein the top portion of the sheet layer includes at least 99% of fluorocarbon by weight.

6. The method of claim 1 , wherein the top portion of the sheet layer has a thickness less than 1 μm.

7. The method of claim 1 , wherein the top portion of the sheet layer has a thickness less than 100 nm.

8. The method of claim 1 , wherein at least 90% of the top portion of the first surface is covered by polytetrafluoroethylene.

9. The method of claim 1 , wherein the sheet layer includes at least 90% of polytetrafluoroethylene by weight.

10. The method of claim 1 , wherein the second structure includes poly carbonates.

11. The method of claim 1 , wherein the second structure includes cyclic olefin polymer or copolymer or polystyrene.

12. The method of claim 1 , wherein a top surface of the sheet layer of the first structure is aligned with a top surface of the second structure.

13. The method of claim 1 , wherein a top surface of the sheet layer of the first structure extends above a top surface of the second structure.

14. The method of claim 1 , wherein a top surface of the sheet layer of the first structure extends below a top surface of the second structure.

15. The method of claim 1 , wherein:

the second structure has a first surface and a second surface that is opposite to the first surface of the second structure;

the first surface of the second structure is adjacent to the first structure;

the first surface of the second structure has a plurality of protrusions; and

a respective protrusion of the plurality of protrusions extends into a respective discrete through-hole of the plurality of discrete through-holes.

16. The method of claim 1 , wherein at least a portion of the first surface of the sheet layer is embedded in the second structure.

17. The method of claim 1 , wherein the second structure includes a base layer and one or more vertical structures along a periphery of the base layer, adjacent to a first surface of the base layer.

18. The method of claim 17 , wherein the one or more vertical structures, the base layer, and the first structure define a reservoir.

19. The method of claim 1 , wherein the first structure includes a hydrophobic material.

20. The method of claim 1 , wherein:

the second structure has a first surface adjacent the first structure; and

the first surface of the second structure has one or more indentations and one or more protrusions in regions corresponding to the plurality of discrete through-holes defined in the sheet layer when the second structure is coupled to the first structure.

Assignments (2)
EXCLUSIVE LICENSE Recorded Jun 30, 2022
From: CURIOX BIOSYSTEMS PTE. LTD
To: CURIOX BIOSYSTEMS CO., LTD.
Reel/Frame 060558/0136 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 12, 2018
From: LIM, ENG SENG; CHEONG, SIAH CHONG; KIM, NAMYONG
To: CURIOX BIOSYSTEMS PTE LTD.
Reel/Frame 045174/0828 →
Continuity (4)
Continuation In Part PCTIB2013000623 · Feb 5, 2013
Provisional Application 61595131 · Feb 5, 2012
Provisional Application 61711127 · Oct 8, 2012
Related Publication 20150017079A1 · Jan 15, 2015