IP Library Granted Patent US 9,968,541
Granted Patent B2
US 9,968,541 · App. 15/277,371 · Granted May 15, 2018

Optical treatment methods

Inventor: Michael P. O'Neil (Dublin, CA)
Assignee: ON Light Sciences Inc.
A61K8/70A61B18/203A61K8/0208A61K31/025A61K41/00A61M35/006A61N5/062A61N5/0616A61Q1/145A61Q19/00A61B2017/00769A61B2018/0047A61B2018/00458A61B2018/00577A61K2800/81
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Quick Facts
Patent No.
US 9,968,541
App. No.
15/277,371
Granted
May 15, 2018
Kind
B2
Abstract

A treatment system and method includes use of a chemical facilitator to provide a result-effective event against one or more negative therapeutic effects related to exposing to a light output a skin portion including a condition treatable in whole or in part with light. In one exemplary embodiment for skin treatment including tattoo removal, perfluorodecalin is used to inhibit or resolve whitening, for example to speed a laser therapy session.

Claims (41)

1. A method of treating a tissue volume including a skin portion comprising:

(a) exposing the skin portion to one or more applications of light from a light-generating device to achieve a desired therapeutic result in the absence of promoting a photodynamic chemical reaction; and

(b) providing a perfluorocarbon to the tissue volume before, during, or after step (a).

2. The method of claim 1 , wherein the perfluorocarbon includes a derivative of decalin.

3. The method of claim 1 , wherein the perfluorocarbon includes perfluorodecalin.

4. The method of claim 1 , wherein each application of light includes a plurality of light pulses.

5. The method of claim 1 , wherein the desired therapeutic result includes ejection of a pigmented substance from the tissue volume.

6. The method of claim 1 , wherein the one or more applications of light include one or more laser sessions.

7. The method of claim 6 , wherein the laser sessions are about four weeks apart.

8. The method of claim 1 , wherein each application of light includes a laser session.

9. The method of claim 8 , wherein each laser session includes one or more laser passes.

10. A method of treating a tissue volume including a skin portion comprising:

(a) exposing the skin portion to one or more applications of light from a light-generating device to achieve a desired therapeutic result in the absence of promoting a photodynamic chemical reaction;

(b) providing a perfluorocarbon to the tissue volume before, during, or after step (a); and

(c) providing cooling for the one or more applications of light.

11. The method of claim 10 , wherein step (c) includes cooling of the skin portion.

12. The method of claim 10 , wherein step (c) includes cooling of the perfluorocarbon.

13. The method of claim 10 , wherein step (c) includes cooling of the light-generating device.

14. The method of claim 10 , wherein step (c) includes cooling of a skin-contacting device.

15. The method of claim 10 , wherein step (c) includes cooling of a patch.

16. A method of treating a tissue volume including a skin portion comprising:

(a) exposing the skin portion to one or more applications of light from a light-generating device to achieve a desired therapeutic result in the absence of promoting a photodynamic chemical reaction; and

(b) providing a perfluorocarbon from a patch or from a vial to the tissue volume before, during, or after step (a).

17. The method of claim 16 , wherein the patch is optically transparent.

18. The method of claim 16 , wherein the patch is moving across the skin portion.

19. A method of treating a tissue volume including a skin portion comprising:

(a) exposing the skin portion to one or more applications of light from a light-generating device to achieve a desired therapeutic result in the absence of promoting a photodynamic chemical reaction; and

(b) providing a perfluorocarbon from a patch to the tissue volume before, during, or after step (a),

wherein the light-generating device includes an emitter, and the emitter is moved across the patch.

20. The method of claim 19 , wherein the patch is disposed in a pouch prior to use.

21. The method of claim 19 , wherein use of the patch results in a reduction of pain as compared to a treatment in which the patch is not used.

22. A method of treating a tissue volume including a skin portion comprising:

(a) exposing the skin portion to one or more applications of light from a light-generating device to achieve a desired therapeutic result in the absence of promoting a photodynamic chemical reaction; and

(b) driving a perfluorocarbon into the tissue volume before, during, or after step (a).

23. The method of claim 22 , wherein the step of driving the perfluorocarbon into the tissue volume includes using vibration.

24. The method of claim 22 , wherein the step of driving the perfluorocarbon into the tissue volume includes using ultrasound.

25. The method of claim 22 , wherein the step of driving the perfluorocarbon into the tissue volume includes using heat.

26. The method of claim 22 , wherein the step of driving the perfluorocarbon into the tissue volume includes using pressure.

27. The method of claim 22 , wherein the step of driving the perfluorocarbon into the tissue volume includes using cooling.

28. The method of claim 22 , wherein the step of driving the perfluorocarbon into the tissue volume includes using a chemical gradient.

29. The method of claim 22 , wherein the step of driving the perfluorocarbon into the tissue volume includes using a chemical action potential.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 27, 2017
From: O'NEIL, MICHAEL P
To: ON LIGHT SCIENCE INC.
Reel/Frame 043709/0988 →
Continuity (7)
Continuation 15201469 · Jul 3, 2016
Continuation 14832398 · Aug 21, 2015
Continuation 13753816 · Jan 30, 2013
Continuation 13436087 · Mar 30, 2012
Provisional Application 61595065 · Feb 4, 2012
Provisional Application 61528130 · Aug 26, 2011
Related Publication 20170027840A1 · Feb 2, 2017