Sebum secretion inhibitory agent
The present invention relates to a novel sebum secretion inhibitor and use thereof for the production of cosmetic and pharmaceutical, notably dermatological, compositions, intended for preventing and/or reducing the secretion of sebum and notably of squalene.
1. A method of cosmetic care for reducing sebum secretion in an individual in need thereof, comprising:
a) identifying on the individual an area of skin having a shiny or greasy appearance due to excessive secretion of sebum; and
b) topically applying onto the area of skin a cosmetic composition comprising an Orthosiphon stamineus extract,
wherein the Orthosiphon stamineus extract is in an amount effective to inhibit or reduce formation of squalene in the area of skin.
2. The method of claim 1 , wherein the skin is normal skin.
3. The method of claim 1 , wherein the area of skin is skin of the face, neck, back, thorax, hands, or chest.
4. The method of claim 1 , wherein the Orthosiphon stamineus extract is obtained from leaves of Orthosiphon stamineus plants.
5. The method of claim 1 , wherein the Orthosiphon stamineus extract is obtained by hot aqueous extraction.
6. The method of claim 1 , wherein the composition contains between about 0.0001% and 10% by weight of the Orthosiphon stamineus extract.
7. The method of claim 1 , wherein the composition contains between about 0.0001% and 5% by weight of the Orthosiphon stamineus extract.
8. The method of claim 1 , wherein the composition is topically applied onto the area of skin daily.
9. The method of claim 1 , wherein the cosmetic composition further comprises a seboregulating agent selected from the group consisting of sarcosine, zinc salicylate, zinc gluconate, azelaic acid, and mixtures thereof.
10. The method of claim 1 , wherein the cosmetic composition further comprises an additional component selected from the group consisting of AHA, a maize extract, an extract of Hibiscus abelmoschus , a fermented soya extract containing peptides, a biotechnologically modified malt extract, a talc, an absorbent polymer, an extract of Boldo, retinoic acid, benzoyl peroxide, erythromycin, clindamycin phosphate and mixtures thereof.
11. The method of claim 1 , wherein the area of skin being treated has reduced and/or delayed shiny appearance.
12. The method of claim 1 , wherein the area of skin being treated has reduced and/or delayed dilatation of pore size.