X-ray/intravascular imaging colocation method and system
In the present invention, a method and associated system is provided that produces a new sequence of combined X-ray/fluoro images obtained in synchrony with intravascular dataset/images. This synchronization is based on the time tags recorded at the acquisition of one dataset of the X-ray/fluoroscopic images and the intravascular images/datasets and the cardiac cycle correspondence between the combined X-ray/fluoro datasets/images. The combined X-ray/fluoro and intravascular sensor images provided in the method for each position of intravascular measurement/slice along the blood vessel allows the physician the ability to determine the planned position of the treatment, e.g., a stent, in the X-ray/fluoro images based on the intravascular images, and allows an accurate assessment of the target/lesion location in the X-ray/fluoro images during treatment.
1. A method for producing enhanced X-ray images of a blood vessel/myocardium, the method comprising the steps of:
obtaining a first set of X-ray images of the blood vessel/myocardium over a single cardiac cycle;
recording a first ECG signal for the single cardiac cycle concurrently with obtaining the first set of X-ray images;
obtaining a second set of X-ray images of the blood vessel/myocardium over a number of cardiac cycles;
recording a second ECG signal for the number of cardiac cycles concurrently with obtaining the second set of X-ray images;
obtaining a set of intravascular images of the blood vessel/myocardium concurrently with obtaining the second set of X-ray images;
synchronizing the set of intravascular images and the second set of X-ray images with regard to the time each of the set of intravascular images and each of the second set of X-ray images was obtained;
selecting one of the set of intravascular images for review after obtaining the set of intravascular images;
reviewing the second set of X-ray images to determine the one of the second set of X-ray images obtained at the same time as the selected one of the set of intravascular images;
reviewing the first ECG signal to determine a first point in the single cardiac cycle at which one of the first set of X-ray images was obtained;
reviewing the second ECG signal to determine a second point within the number of cardiac cycles that the one of the second set of X-ray images obtained at the same time as the selected one of the set of intravascular images was obtained, wherein the second point closely corresponds to the first point in their respective positions within the respective cardiac cycles; and
overlaying the one of the first set of X-ray images taken at the first point with the one of the second set of X-ray images taken at the second point to form the combined X-ray image.
2. The method of claim 1 , wherein the step of overlaying the one of the first set of X-ray images with the one of the second set of X-ray images comprises processing at least one of the one of the first set of X-ray images or the one of the second set of X-ray images.
3. The method of claim 2 , wherein the step of processing at least one of the one of the first set of X-ray images or the one of the second set of X-ray images comprises applying an image processing filter to the one of the second set of X-ray images that enhances curvilinear structures.
4. The method of claim 2 , wherein the step of processing at least one of the one of the first set of X-ray images or the one of the second set of X-ray images comprises distorting the one of the second set of X-ray images in a known manner to compensate for motion of the blood vessels/myocardium induced by respiration.
5. The method of claim 2 , wherein the step of processing at least one of the one of the first set of X-ray images or the one of the second set of X-ray images comprises the steps of:
combining the first set of X-ray images to form a small video loop covering the single cardiac cycle; and
overlaying each of the second set of X-ray images with the one of the first set of X-ray images corresponding to their respective positions within the respective cardiac cycles to form a video of the sequence of multiple cardiac cycles covered by the second set of X-ray images.
6. The method of claim 1 , wherein the step overlaying the one of the first set of X-ray images taken at the first point with the one of the second set of X-ray images taken at the second point comprises overlaying the entire first set of X-ray images with the entire second set of X-ray images.
7. The method of claim 1 further comprising the step of displaying the combined X-ray image in conjunction with the selected one of the set of intravascular images.
8. The method of claim 7 wherein the step of displaying the combined X-ray image in conjunction with the selected one of the set of intravascular images comprises displaying the combined X-ray image, the selected one of the set of intravascular images and a stacked roadmap image combining all of the set of intravascular images.
9. The method of claim 1 , wherein the step overlaying the one of the first set of X-ray images taken at the first point with the one of the second set of X-ray images taken at the second point comprises overlaying the one of the first set of X-ray images taken at the first point with each of the second set of X-ray images to form a number of combined X-ray images.
10. A method for producing enhanced X-ray images of a blood vessel/myocardium, the method comprising the steps of:
obtaining a first set of X-ray images of the blood vessel/myocardium over a single cardiac cycle;
obtaining a second set of X-ray images of the blood vessel/myocardium over a number of cardiac cycles;
synchronizing the second set of X-ray images and the first set of X-ray images with regard to the portion of the cardiac cycle at which each image was obtained; and
overlaying one of the first set of X-ray images with each of the second set of X-ray images to form a number of combined X-ray images on a display.
11. The method of claim 10 further comprising the step of injecting a contrast agent into the blood vessel/myocardium prior to obtaining the first set of X-ray images.
12. An imaging system for performing a method for producing enhanced X-ray images of a blood vessel/myocardium, the method comprising the steps of:
obtaining a first set of X-ray images of the blood vessel/myocardium over a single cardiac cycle;
obtaining a second set of X-ray images of the blood vessel/myocardium over a number of cardiac cycles;
obtaining a set of intravascular images of the blood vessel/myocardium concurrently with obtaining the second set of X-ray images;
synchronizing the set of intravascular images and the second set of X-ray images with regard to the time each of the set of intravascular images and each of the second set of X-ray images was obtained;
overlaying one of the first set of X-ray images with each of the second set of X-ray images to produce combined X-ray images on a display;
selecting one of the set of intravascular images for review after obtaining the set of intravascular images; and
reviewing the second set of X-ray images to determine the one of the second set of X-ray images obtained at the same time as the selected one of the set of intravascular images.
13. The imaging system of claim 12 , wherein said system:
records a first ECG signal for the single cardiac cycle concurrently with obtaining the first set of X-ray images; and
records a second ECG signal for the number of cardiac cycles concurrently with obtaining the second set of X-ray images.