Strain of
The invention relates to a novel strain of Bifidobacterium animals ssp. animalis , which is able, inter alia, to improve the function of the enteric nervous system, and to compositions said novel strain.
1. A composition comprising the Bifidobacterium animalis subspecies animalis strain deposited on 6 Mar. 2012 under number I-4602 with the CNCM ( Collection Nationale de Cultures de Microorganismes ) (strain Bifidobacterium animalis subspecies animalis CNCM I-4602), wherein the composition is a fermented dairy food product.
2. The composition according to claim 1 , wherein the composition comprises at least 10 5 cfu, per g dry weight, of the strain Bifidobacterium animalis ssp. animalis CNCM I-4602.
3. The composition according to claim 1 , wherein the composition comprises at least 10 6 cfu, per g dry weight, of the strain Bifidobacterium animalis ssp. animalis CNCM I-4602.
4. A method of preventing and/or reducing gastro-intestinal discomfort or gastro-intestinal disorders, comprising administering the strain Bifidobacterium animalis subspecies animalis CNCM I-4602 to a subject in need thereof.
5. The method of claim 4 , wherein the strain is administered to a subject having a disorder selected from the group consisting of an intestinal motility disorder, an intestinal permeability disorder, irritable bowel syndrome (IBS), inflammatory bowel disease (IBD), constipation, and intestinal infections.
6. A method of preventing and/or reducing gastro-intestinal discomfort or gastro-intestinal disorders, comprising administering a composition according to claim 1 to a subject in need thereof.
7. The method of claim 6 , wherein the composition is administered to a subject having a disorder selected from the group consisting of an intestinal motility disorder, an intestinal permeability disorder, irritable bowel syndrome (IBS), inflammatory bowel disease (IBD), constipation, and intestinal infections.
8. A method of increasing vaso-active intestinal peptide (VIP) levels of the enteric nervous system in a subject, comprising administering the strain Bifidobacterium animalis subspecies animalis CNCM I-4602 to a subject in need thereof.
9. A method of increasing vaso-active intestinal peptide (VIP) levels of the enteric nervous system in a subject, comprising administering a composition according to claim 1 to a subject in need thereof.
10. A method of improving gastro-intestinal motility, improving intestinal peristalsis and/or decreasing intestinal permeability, comprising administering the strain Bifidobacterium animalis subspecies animalis CNCM I-4602 to a subject in need thereof.
11. A method of improving gastro-intestinal motility, improving intestinal peristalsis and/or decreasing intestinal permeability, comprising administering a composition according to claim 1 to a subject in need thereof.